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3-(4-chlorophenyl)-5-(1-piperidylmethyl)isoxazole

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Identification
Molecular formula
C17H17ClN2O
CAS number
78955-92-3
IUPAC name
3-(4-chlorophenyl)-5-(1-piperidylmethyl)isoxazole
State
State

At room temperature, this compound is typically found in a solid state, indicative of many organic compounds with a complex structure and significant molecular weight.

Melting point (Celsius)
184.00
Melting point (Kelvin)
457.00
Boiling point (Celsius)
472.00
Boiling point (Kelvin)
745.00
General information
Molecular weight
248.72g/mol
Molar mass
248.7240g/mol
Density
1.2000g/cm3
Appearence

The compound is typically a crystalline solid with light color, possibly ranging from white to off-white. It has a subtle aromatic odor characteristic of many aromatic organic compounds.

Comment on solubility

Solubility of 3-(4-chlorophenyl)-5-(1-piperidylmethyl)isoxazole

The solubility of 3-(4-chlorophenyl)-5-(1-piperidylmethyl)isoxazole can be characterized by several key factors:

  • Solvent Dependency: This compound's solubility is significantly affected by the choice of solvent. Common organic solvents such as ethanol, dimethyl sulfoxide (DMSO), and acetone often dissolve this compound efficiently.
  • Temperature Influence: As with many organic compounds, an increase in temperature typically enhances solubility. Elevated temperatures enable greater molecular movement, facilitating interactions with solvents.
  • Polarity Considerations: Given the presence of polar functional groups, the solubility in polar solvents tends to be better in comparison to nonpolar solvents. The piperidyl moiety may contribute to increased solubility due to hydrogen bonding capabilities.

While quantitative solubility data may vary, it is generally understood that the attainment of solubility for this compound occurs within the range expected for similar isoxazole derivatives. In summary, selecting appropriate solvents and considering temperature adjustments will yield the best results concerning the solubility of 3-(4-chlorophenyl)-5-(1-piperidylmethyl)isoxazole.

Interesting facts

Interesting Facts about 3-(4-chlorophenyl)-5-(1-piperidylmethyl)isoxazole

This compound, known as 3-(4-chlorophenyl)-5-(1-piperidylmethyl)isoxazole, is a fascinating member of the isoxazole family, a class of heterocyclic compounds with versatile applications in medicinal chemistry.

Chemical Significance

  • Isoxazole Structure: The isoxazole ring features a five-membered cyclic structure containing both nitrogen and oxygen atoms, contributing to the compound's unique chemical properties.
  • Functional Groups: This compound contains a piperidine group, which is known for its presence in various pharmaceuticals, enhancing interactions at biological receptors.
  • Chlorophenyl Substitution: The 4-chlorophenyl group may play a role in modifying the compound's electronic properties and hydrophobicity, often influencing its binding affinity to target proteins.

Biological Relevance

  • Potential Therapeutic Applications: Compounds like this one are often investigated for their potential in treating neurological disorders, given their structural features that may enhance central nervous system activity.
  • Research Studies: Studies have explored the pharmacological profiles of isoxazole derivatives, revealing their potential as inhibitors, antitumor agents, and agents for pain management.
  • Mechanistic Insights: Understanding the mechanisms by which this compound interacts with biological targets can offer insights for developing new drug therapies.

In conclusion, 3-(4-chlorophenyl)-5-(1-piperidylmethyl)isoxazole is more than just a chemical compound; it represents a rich avenue for research and discovery in medicinal chemistry. As scientists continue to explore its properties, who knows what remarkable applications may arise?