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Cloperastine

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Identification
Molecular formula
C21H26ClN
CAS number
3703-76-2
IUPAC name
3-[(4-chlorophenyl)methyl]-1,8,8-trimethyl-3-azabicyclo[3.2.1]octane
State
State

At room temperature, Cloperastine is typically found in a solid state.

Melting point (Celsius)
93.00
Melting point (Kelvin)
366.15
Boiling point (Celsius)
409.15
Boiling point (Kelvin)
682.30
General information
Molecular weight
344.90g/mol
Molar mass
344.8850g/mol
Density
1.1510g/cm3
Appearence

Cloperastine appears as a white crystalline powder. It does not have a distinctive color and is often odorless.

Comment on solubility

Solubility of 3-[(4-chlorophenyl)methyl]-1,8,8-trimethyl-3-azabicyclo[3.2.1]octane

The solubility of 3-[(4-chlorophenyl)methyl]-1,8,8-trimethyl-3-azabicyclo[3.2.1]octane in various solvents can significantly influence its applications and effectiveness. Its solubility characteristics can be summarized as follows:

  • Polar Solvents: Generally, compounds with polar functional groups tend to dissolve well in polar solvents like water or alcohols. However, the presence of the bulky trimethyl and chlorophenyl moieties suggests that this compound may have limited solubility in highly polar solvents.
  • Non-Polar Solvents: Given the hydrophobic nature from the significant alkyl chain and aromatic groups, this compound is likely to show better solubility in non-polar solvents such as hexane or chloroform.
  • Temperature Influence: Solubility can increase with temperature. Thus, higher temperatures may enhance the solubility of this compound in appropriate solvents.
  • pH Levels: If the compound possesses purifications that are sensitive to pH, solubility might also be affected; thus, thorough testing in various pH conditions can provide insights into its behavior in different environments.

In conclusion, while the solubility of 3-[(4-chlorophenyl)methyl]-1,8,8-trimethyl-3-azabicyclo[3.2.1]octane is expected to be better in non-polar solvents, it is essential to conduct empirical testing in various solvents and conditions to gain definitive insights into its solubility profile.

Interesting facts

Interesting Facts about 3-[(4-chlorophenyl)methyl]-1,8,8-trimethyl-3-azabicyclo[3.2.1]octane

This compound, also known for its complex bicyclic structure, belongs to a family of molecules that can exhibit significant biological activity. Here are some engaging insights about this intriguing compound:

  • Structural Complexity: The presence of both bicyclic and chlorophenyl moieties in its structure makes this compound a fascinating subject of study, particularly in the field of medicinal chemistry.
  • Pharmacological Potential: Compounds with similar structures are often investigated for their potential as pharmacological agents, including roles in the treatment of neurodegenerative disorders.
  • Synthetic Challenges: The synthesis of bicyclic compounds like this one often poses unique challenges due to their complex ring structures, which require careful selection of starting materials and reagents.
  • Biological Activity: Certain derivatives of azabicyclo compounds have been shown to exhibit interaction with neurotransmitter systems, suggesting potential cognitive and therapeutic effects.
  • Research Significance: As researchers explore more about the functional groups in such compounds, they can unlock new therapeutic pathways, making this compound significant in broader scientific research.

In summary, the study of 3-[(4-chlorophenyl)methyl]-1,8,8-trimethyl-3-azabicyclo[3.2.1]octane not only emphasizes the diversity and complexity of chemical compounds but also highlights the potential for innovation in drug development and design.