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Clidinium Bromide

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Identification
Molecular formula
C22H26Cl2N
CAS number
7018-74-6
IUPAC name
3-[(4-chlorophenyl)methyl]-1,8,8-trimethyl-3-azoniabicyclo[3.2.1]octane;chloride
State
State

At room temperature, clidinium bromide is in a solid state.

Melting point (Celsius)
208.00
Melting point (Kelvin)
481.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
354.95g/mol
Molar mass
354.9510g/mol
Density
1.0300g/cm3
Appearence

This compound typically appears as a white or off-white crystalline powder. It is without significant odor and has a solid form, typical of many pharmaceutically used compounds.

Comment on solubility

Solubility of 3-[(4-chlorophenyl)methyl]-1,8,8-trimethyl-3-azoniabicyclo[3.2.1]octane;chloride

The solubility of 3-[(4-chlorophenyl)methyl]-1,8,8-trimethyl-3-azoniabicyclo[3.2.1]octane;chloride is predominantly influenced by its ionic nature, stemming from its azoniabicyclic structure. Typically, salts of this kind exhibit higher solubility in polar solvents, primarily due to the capacity of water molecules to stabilize the ions through solvation.

Key Factors Affecting Solubility:

  • Polarity: The presence of chloride anion enhances solubility in water, as ionic interactions are favorable in polar environments.
  • Hydrogen Bonding: While individual ionic species dissolve well, additional hydrogen-bonding capability may slightly improve solubility in various organic solvents.
  • Temperature: Increasing temperature generally favors solubility for most ionic compounds due to enhanced molecular movement.

In aqueous solutions, one could assert that this compound is likely to be considerably soluble, but the extent may vary based on specific conditions like pH and ionic strength. It is crucial to bear in mind that the solubility can be further affected by the concentration of the other components in the solution, leading to complex interactions that modulate the behavior of the compound in diverse settings.

Overall, understanding the solubility characteristics of this compound is essential not only for its practical applications but also for comprehending its behavior in biological and environmental contexts.

Interesting facts

Interesting Facts about 3-[(4-chlorophenyl)methyl]-1,8,8-trimethyl-3-azoniabicyclo[3.2.1]octane;chloride

This compound, known for its complex structure and distinctive properties, opens up a fascinating realm of study in organic and medicinal chemistry. Here are some intriguing aspects:

  • Quaternary Ammonium Compound: As a quaternary ammonium derivative, this compound features a positively charged nitrogen atom, making it particularly interesting for various biological and pharmacological applications.
  • Biological Activity: Compounds of this nature often exhibit significant biological activity, making them potential candidates for drug development. The presence of the 4-chlorophenyl group can enhance binding affinity to biological targets.
  • Chirality: The bicyclic structure contributes to the chirality of the compound, which is essential in the context of drug design. Chiral compounds can have drastically different effects in biological systems, underscoring the importance of stereochemistry in pharmaceuticals.
  • Use in Synthesis: This compound may also serve as an intermediate in the synthesis of more complex organic molecules, showcasing its utility in synthetic organic chemistry.
  • Psychoactive Potential: Given its structure, it bears resemblance to amphetamines and other psychoactive agents, leading to intriguing discussions around its potential effects on the central nervous system.

In summary, the study of 3-[(4-chlorophenyl)methyl]-1,8,8-trimethyl-3-azoniabicyclo[3.2.1]octane;chloride not only emphasizes the intricacies of organic synthesis, but also highlights the vital intersection between molecular structure and biological activity. As one engages with this compound, one can appreciate the depth of potential it holds within the vast landscape of chemical research.

Synonyms
3-(p-Chlorobenzyl)-1,8,8-trimethyl-3-azabicyclo(3.2.1)octane hydrochloride
1220-30-0
3-AZABICYCLO(3.2.1)OCTANE, 3-(p-CHLOROBENZYL)-1,8,8-TRIMETHYL-, HYDROCHLORIDE