3-(4-ethoxy-3-methyl-phenyl)prop-2-enehydroxamic acid

Identification

Molecular formula

C₁₂H₁₅NO₃

CAS number

Not available

IUPAC name

3-(4-ethoxy-3-methyl-phenyl)prop-2-enehydroxamic acid

State

At room temperature, 3-(4-ethoxy-3-methyl-phenyl)prop-2-enehydroxamic acid is in a solid state. It has a crystalline structure and is stable under normal conditions.

Melting point (Celsius)

126.70

Melting point (Kelvin)

399.80

Boiling point (Celsius)

275.50

Boiling point (Kelvin)

548.60

General information

Molecular weight

221.29g/mol

Molar mass

221.2870g/mol

Density

1.1234g/cm³

Appearence

3-(4-ethoxy-3-methyl-phenyl)prop-2-enehydroxamic acid typically appears as an off-white to pale yellow crystalline solid. The compound's crystalline structure is quite distinct and noticeable under a microscope, with well-defined edges.

Comment on solubility

Solubility of 3-(4-ethoxy-3-methyl-phenyl)prop-2-enehydroxamic acid

The solubility of 3-(4-ethoxy-3-methyl-phenyl)prop-2-enehydroxamic acid is influenced by various factors that include its chemical structure and the nature of the solvent. Understanding its solubility can provide insights into its potential applications in different fields.

Polarity: The presence of both hydrophilic (–OH) and hydrophobic (aromatic) groups in the compound creates a balance that can affect solubility positively in polar solvents like water and negatively in non-polar solvents.
Hydrogen Bonding: The hydroxamic acid functional group is capable of donating and accepting hydrogen bonds, enhancing solubility in polar solvents.
Concentration Effects: At higher concentrations, solubility may decrease due to precipitation or intermolecular interactions causing aggregation.

In general, it is anticipated that 3-(4-ethoxy-3-methyl-phenyl)prop-2-enehydroxamic acid would demonstrate moderate solubility in water due to the competing influences of its functional groups. It is essential to conduct experimental determinations to establish precise solubility parameters under varying conditions.

Interesting facts

Exploring 3-(4-ethoxy-3-methyl-phenyl)prop-2-enehydroxamic acid

3-(4-ethoxy-3-methyl-phenyl)prop-2-enehydroxamic acid is a fascinating compound owing to its unique structure and potential applications in various fields. As a chemical compound with a hydroxamic acid functional group, it offers interesting properties that can be of great relevance in medicinal chemistry and organic synthesis.

Interesting Characteristics:

Versatile Functional Group: The hydroxamic acid moiety is known for its reactivity, particularly as a ligand in coordination chemistry, making this compound a potential candidate for development in pharmaceutical applications.
Anticancer Potential: Compounds with similar hydroxamic acid functionalities have been studied for their ability to inhibit histone deacetylases (HDACs), which are implicated in various cancers. This opens up avenues for research into the therapeutic applications of this molecule.
Synthetic Routes: The synthesis of this compound can involve various organic reactions such as alkylation and amidation, highlighting the compound's relevance in teaching organic synthesis techniques.
Structure-Activity Relationship (SAR): Understanding how alterations in the structure of 3-(4-ethoxy-3-methyl-phenyl)prop-2-enehydroxamic acid affect its biological activity could lead to the design of more effective derivatives.

In summary, 3-(4-ethoxy-3-methyl-phenyl)prop-2-enehydroxamic acid is not only a compound of interest for its structural features but also a potential player in the development of new therapeutic agents. Ongoing research in this area could uncover significant health benefits and further applications in the fields of chemistry and medicine.