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Identification
Molecular formula
C15H15FO3
CAS number
1264696-24-7
IUPAC name
3-[(4-fluorophenyl)methyl]-4-(prop-2-ynoxymethyl)tetrahydrofuran-2-one
State
State
The compound is a liquid at room temperature. It remains stable under standard conditions but should be handled with appropriate safety measures due to its reactive functionalities.
Melting point (Celsius)
-12.00
Melting point (Kelvin)
261.15
Boiling point (Celsius)
238.00
Boiling point (Kelvin)
511.15
General information
Molecular weight
248.26g/mol
Molar mass
248.2620g/mol
Density
1.2150g/cm3
Appearence

Typically, the compound appears as a colorless or pale yellow liquid. The detailed structure, featuring a tetrahydrofuran ring and aromatic components, suggests it may exhibit a slight aromatic odour.

Comment on solubility

Solubility of 3-[(4-fluorophenyl)methyl]-4-(prop-2-ynoxymethyl)tetrahydrofuran-2-one

The solubility of 3-[(4-fluorophenyl)methyl]-4-(prop-2-ynoxymethyl)tetrahydrofuran-2-one exhibits some intriguing characteristics, particularly due to its complex molecular structure. Here are some key points to consider:

  • Polar and Nonpolar Regions: The compound features a blend of polar (tetrahydrofuran) and nonpolar (4-fluorophenyl) functional groups, which may influence its solubility in various solvents.
  • Solvent Compatibility: It is expected to show better solubility in polar solvents like ethanol or dimethyl sulfoxide (DMSO) than in nonpolar solvents, due to the polar nature of the tetrahydrofuran moiety.
  • Hydrophobic Interactions: The presence of the 4-fluorophenyl group may introduce hydrophobic interactions, which could hinder solubility in certain aqueous environments.
  • Temperature Dependence: Solubility may also be temperature-dependent, as increased temperatures typically enhance the solubility of organic compounds.

In conclusion, while the solubility of 3-[(4-fluorophenyl)methyl]-4-(prop-2-ynoxymethyl)tetrahydrofuran-2-one may vary across solvents, understanding these interactions is key to predicting practical applications and effective use in laboratory or industrial settings. Always consider the context of use when evaluating solubility properties.

Interesting facts

Interesting Facts about 3-[(4-Fluorophenyl)methyl]-4-(prop-2-ynoxymethyl)tetrahydrofuran-2-one

This compound is a fascinating member of the tetrahydrofuran family, known for its unique structural characteristics and potential applications in various fields. Here are some intriguing insights:

  • Synthetic Route: The synthesis of this compound often involves complex organic reactions that may include methods like nucleophilic substitution and various coupling reactions. These methods showcase the ingenuity of modern organic chemistry.
  • Fluorine's Influence: The presence of the fluorophenyl group can significantly affect the compound's electronic properties, making it a useful benchmark for researchers exploring drug interactions or chemical reactivity.
  • Pharmacological Potential: Compounds similar to this one have been studied for their pharmaceutical properties. The incorporation of complex substituents like the prop-2-ynoxymethyl group may enhance bioactivity and target specificity in medicinal chemistry.
  • Polyfunctional characteristics: The combination of both cyclic and acyclic structures within this compound opens up numerous pathways for further functionalization, potentially leading to novel derivatives.
  • Research Interest: This compound may attract attention in studies related to organic materials and their applications in fields such as drug development and the creation of advanced materials.

In summary, 3-[(4-Fluorophenyl)methyl]-4-(prop-2-ynoxymethyl)tetrahydrofuran-2-one serves as a prime example of the intricate relationships between structure and function in chemistry. It embodies the excitement of discovering new molecular interactions and the endless possibilities that lie within organic synthesis.

Synonyms
BRN 1589743
27850-30-2
Dihydro-3-(p-fluorobenzyl)-5-(2-propynyloxymethyl)-2(3H)-furanone
Propargyloxymethyl-4 p-fluorobenzyl-2 gamma-butyrolactone
gamma-Butyrolactone, 2-(p-fluorobenzyl)-4-(2-propynyloxymethyl)-
2(3H)-FURANONE, DIHYDRO-3-(p-FLUOROBENZYL)-5-(2-PROPYNYLOXYMETHYL)-
RefChem:241635
DTXSID30950524
3-[(4-Fluorophenyl)methyl]-4-{[(prop-2-yn-1-yl)oxy]methyl}oxolan-2-one