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3-(4-iodophenyl)-1-phenyl-isothiourea

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Identification
Molecular formula
C13H11IN2S
CAS number
NA
IUPAC name
3-(4-iodophenyl)-1-phenyl-isothiourea
State
State
This compound is in a solid state at room temperature. It remains stable under normal conditions, but it should be stored in a dark, dry area to prevent any decomposition or reaction with moisture.
Melting point (Celsius)
142.30
Melting point (Kelvin)
415.45
Boiling point (Celsius)
307.20
Boiling point (Kelvin)
580.35
General information
Molecular weight
351.14g/mol
Molar mass
351.1380g/mol
Density
1.7408g/cm3
Appearence

3-(4-Iodophenyl)-1-phenyl-isothiourea typically appears as a solid crystalline compound. The crystals are often colorless to pale yellow, though variations can occur based on purity and method of preparation.

Comment on solubility

Solubility of 3-(4-iodophenyl)-1-phenyl-isothiourea

The solubility of 3-(4-iodophenyl)-1-phenyl-isothiourea can be quite fascinating, influenced by various factors including temperature and the presence of solvents. Overall, this compound exhibits **moderate** solubility in organic solvents while showing ***limited*** solubility in water. Here are some key points regarding its solubility:

  • Organic Solvents: The compound is more likely to dissolve in non-polar or slightly polar organic solvents such as ethanol, acetone, and DMSO. This property can be attributed to its aromatic structure and the presence of iodine, which enhances solvation in organic media.
  • Water Solubility: 3-(4-iodophenyl)-1-phenyl-isothiourea is expected to be sparingly soluble in water due to its hydrophobic characteristics, including the large hydrophobic phenyl groups.
  • Temperature Effects: Generally, increasing the temperature may improve solubility in organic solvents but has a negligible effect in water where solubility is inherently limited.

In practical applications, choosing the right solvent is essential for maximizing the compound's effectiveness, particularly in synthetic routes or biological testing. Therefore, understanding its solubility profile can significantly impact its usage and handling. As noted, while it potentially dissolves well in organic mediums, one must always conduct preliminary solubility tests to confirm specific conditions before practical application.

Interesting facts

Interesting Facts about 3-(4-iodophenyl)-1-phenyl-isothiourea

3-(4-iodophenyl)-1-phenyl-isothiourea is a fascinating compound that falls into the category of isothioureas, which are known for their diverse applications in medicinal chemistry and agrochemicals. Here are some intriguing aspects of this compound:

  • Structure Diversity: The presence of both an iodine atom and a phenyl group in its structure suggests potential for unique reactivity and interaction with biological systems.
  • Applications in Agriculture: Compounds of this type can act as herbicides and fungicides, showing promise in protecting crops against various pathogens.
  • Medicinal Potential: Isothioureas are being explored for their anti-cancer properties, as they can inhibit certain cancer cell growth. The modifications in this compound could lead to improved efficacy in treatments.
  • Research Utility: The compound serves as a useful tool in research settings, especially in studying the mechanisms of enzymatic actions and interactions in biochemistry.
  • Colorimetric Reactivity: Some isothioureas exhibit colors that change upon reaction with different agents, making them useful in analytical chemistry for visual detection methods.

Furthermore, the impact of iodine on the compound's biological activity cannot be overstated; it can enhance the lipophilicity of the molecule, potentially leading to increased cell membrane permeability. Scientists typically emphasize the significance of structural modifications in understanding and harnessing the capabilities of such compounds.

In summary, 3-(4-iodophenyl)-1-phenyl-isothiourea embodies the synergy of structural complexity and functional variability. The ongoing research into compounds of this nature illustrates the endless possibilities in both agriculture and medicine.