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Apigenin 7-acetate

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Identification
Molecular formula
C24H16O5
CAS number
61276-16-2
IUPAC name
[3-(4-methoxyphenyl)-2-oxo-4-phenyl-chromen-7-yl] acetate
State
State
At room temperature, Apigenin 7-acetate exists as a crystalline solid.
Melting point (Celsius)
280.00
Melting point (Kelvin)
553.00
Boiling point (Celsius)
555.00
Boiling point (Kelvin)
828.00
General information
Molecular weight
356.37g/mol
Molar mass
356.3710g/mol
Density
1.3800g/cm3
Appearence

Apigenin 7-acetate typically appears as a solid, crystalline powder. The color can vary, often being off-white to light beige.

Comment on solubility

Solubility of [3-(4-methoxyphenyl)-2-oxo-4-phenyl-chromen-7-yl] acetate

The solubility of [3-(4-methoxyphenyl)-2-oxo-4-phenyl-chromen-7-yl] acetate can be influenced by various factors, primarily due to its complex structure. Generally, the solubility of this compound can be summarized as follows:

  • Organic Solvents: It is likely to be soluble in organic solvents such as ethanol, dichloromethane, and acetone, which can facilitate the dissolution of aromatic compounds.
  • Water: Given that this compound contains a significant number of aromatic rings, its solubility in water is expected to be low. Aromatic compounds often exhibit poor solubility in polar solvents.
  • Temperature: Increased temperature may enhance the solubility, as it typically allows for greater molecular movement and interactions.

In regards to its solubility:

  • The presence of the methoxy group can enhance solubility in non-polar solvents by providing a hydrophobic interaction.
  • However, the overall rigidity of the chromenyl structure may hinder complete solubility.

Therefore, it is crucial to understand that:

  • "Solubility is like understanding a song; you need to know both the lyrics and the melody to appreciate it fully."

In conclusion, [3-(4-methoxyphenyl)-2-oxo-4-phenyl-chromen-7-yl] acetate is likely to be more soluble in organic solvents than in water, making it more versatile in organic reactions and applications.

Interesting facts

Exploring [3-(4-methoxyphenyl)-2-oxo-4-phenyl-chromen-7-yl] Acetate

[3-(4-methoxyphenyl)-2-oxo-4-phenyl-chromen-7-yl] acetate is a fascinating compound that belongs to the family of flavonoids, a class of polyphenolic compounds notable for their diverse biological activities. Flavonoids are not just aesthetically pleasing; they serve crucial roles in the plant kingdom, acting as pigments and contributing to plant protection against UV radiation and pests.

Key Characteristics

  • Biological Activity: Research suggests that derivatives of flavonoids can exhibit a wide range of biological activities including antioxidant, anti-inflammatory, and anti-cancer properties.
  • Pharmacological Potential: Studies have indicated that compounds like [3-(4-methoxyphenyl)-2-oxo-4-phenyl-chromen-7-yl] acetate may contribute to therapeutic effects in various diseases due to their capability to modulate cellular pathways.
  • Natural Sources: Many flavonoids are derived from fruits, vegetables, and herbs, making them an integral part of dietary health and wellness.

In the chemistry community, the synthetic routes to produce such compounds are highly valued. The synthesis of [3-(4-methoxyphenyl)-2-oxo-4-phenyl-chromen-7-yl] acetate often involves multi-step organic synthesis techniques, demonstrating the complexity and beauty of organic chemistry.

One of the most intriguing aspects of flavonoids, including this compound, is their structure-activity relationship (SAR). Understanding how variations in chemical structure affect biological activity is a key focus in medicinal chemistry and can lead to the discovery of novel therapeutic agents.

In the words of a renowned chemist, "To study the structure of compounds is to understand the fabric of life itself." This quote resonates deeply in the exploration of compounds like [3-(4-methoxyphenyl)-2-oxo-4-phenyl-chromen-7-yl] acetate, as it highlights the connection between chemical configuration and biological impact.

In summary, [3-(4-methoxyphenyl)-2-oxo-4-phenyl-chromen-7-yl] acetate stands out not only for its complex structure but also for its potential in pharmacology, making it a subject of great interest in the fields of chemistry and medicine.

Synonyms
COUMARIN, 7-HYDROXY-3-(p-METHOXYPHENYL)-4-PHENYL-, ACETATE (ester)
1508-88-9
BRN 1298475
7-Hydroxy-3-(p-methoxyphenyl)-4-phenylcoumarin acetate (ester)
SB8N3TVK7G
DTXSID60164612
7-(Acetyloxy)-3-(4-methoxyphenyl)-4-phenyl-2H-1-benzopyran-2-one
2H-1-Benzopyran-2-one, 7-(acetyloxy)-3-(4-methoxyphenyl)-4-phenyl-