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3-(4-methoxyphenyl)-4-methyl-1H-imidazol-2-one

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Identification
Molecular formula
C11H12N2O2
CAS number
53700-74-8
IUPAC name
3-(4-methoxyphenyl)-4-methyl-1H-imidazol-2-one
State
State

The compound is a solid at room temperature.

Melting point (Celsius)
147.50
Melting point (Kelvin)
420.65
Boiling point (Celsius)
356.10
Boiling point (Kelvin)
629.25
General information
Molecular weight
204.22g/mol
Molar mass
204.2210g/mol
Density
1.1920g/cm3
Appearence

The compound is a solid under standard conditions. It typically crystallizes in crystalline form and is off-white to light brown in color. The appearance can vary depending on the purity and preparation method.

Comment on solubility

Solubility of 3-(4-methoxyphenyl)-4-methyl-1H-imidazol-2-one

The solubility of 3-(4-methoxyphenyl)-4-methyl-1H-imidazol-2-one exhibits some interesting characteristics that highlight its chemical behavior in various solvents. This compound can be noted for:

  • Moderate Solubility in Organic Solvents: It is likely to dissolve well in organic solvents such as ethanol and dimethyl sulfoxide (DMSO), which are effective in solubilizing organic compounds due to their polar characteristics.
  • Limited Solubility in Water: Given the presence of the imidazole moiety, the overall solubility in water may be rather low. The nonpolar regions of the methoxyphenyl group can contribute to hydrophobic interactions, further decreasing solubility in aqueous media.
  • Effect of Temperature: Like many organic compounds, the solubility may increase with temperature. Thus, adjusting the temperature can provide a useful method to enhance its solubility in specific solvents.

In conclusion, while the solubility characteristics of 3-(4-methoxyphenyl)-4-methyl-1H-imidazol-2-one might limit its utility in aqueous systems, its behavior in organic solvents opens up various pathways for applications in pharmaceutical and research domains. Understanding these solubility traits can aid in better formulation and utilization of this compound in practical settings.

Interesting facts

Exploring 3-(4-Methoxyphenyl)-4-methyl-1H-imidazol-2-one

3-(4-Methoxyphenyl)-4-methyl-1H-imidazol-2-one is a fascinating compound that offers a variety of interesting aspects for chemists and researchers alike. Here are some noteworthy points about this compound:

  • Chemical Structure: Its structure features an imidazole ring, known for its versatility in biological applications, allowing for a wide range of activities, such as antimicrobial and anti-inflammatory properties.
  • Medicinal Significance: Compounds with imidazole moieties have been explored extensively in pharmaceuticals. This particular compound is thought to have potential therapeutic applications, making it a point of interest in drug development.
  • Substituent Influence: The presence of the methoxy group (-OCH3) in the para position significantly influences its electronic properties, potentially enhancing its reactivity and solubility, thus impacting biological interactions.
  • Synthesis Challenges: The synthesis of such compounds often requires careful control of reaction conditions, showcasing the intricate dance of organic chemistry where slight variations can lead to completely different products.
  • Research Applications: Ongoing studies may focus on how subtle changes in the compound’s structure can lead to different pharmacological profiles, opening avenues for the development of new drugs.
  • Collaboration Across Disciplines: The study of this compound exemplifies interdisciplinary approaches involving chemistry, biology, and material science, showcasing its relevance beyond traditional boundaries.

As scientists continue to delve deeper into the characteristics and applications of 3-(4-Methoxyphenyl)-4-methyl-1H-imidazol-2-one, they may uncover even more remarkable properties that contribute to its potential as a useful chemical tool in various research fields. Overall, the ongoing exploration of such compounds highlights the dynamic and evolving nature of chemical science.

Synonyms
METAZAMIDE
14058-90-3
Metazamide [INN]
Metazamidum
GPA-878
metazamida
UNII-T3Y0F5VOB8
T3Y0F5VOB8
GPA 878
DTXSID80161441
1-(4-Methoxyphenyl)-5-methyl-4-imidazolin-2-on
1-(p-Methoxyphenyl)-5-methyl-4-imidazolin-2-one
4-Imidazolin-2-one, 1-(4-methoxyphenyl)-5-methyl-
DTXCID3083932
3-(4-methoxyphenyl)-4-methyl-1H-imidazol-2-one
1-(4-methoxyphenyl)-5-methyl-2,3-dihydro-1H-imidazol-2-one
Metazamid
SCHEMBL193544
CHEMBL2104723
AKOS017548002
NS00125044
EN300-255063
G51845
Q27289634
Z1450948336