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3-(4-Methoxyphenyl)prop-2-enehydroxamic acid

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Identification
Molecular formula
C10H11NO3
CAS number
Not registered
IUPAC name
3-(4-methoxyphenyl)prop-2-enehydroxamic acid
State
State

At room temperature, the compound exists as a solid.

Melting point (Celsius)
150.00
Melting point (Kelvin)
423.15
Boiling point (Celsius)
340.00
Boiling point (Kelvin)
613.15
General information
Molecular weight
193.21g/mol
Molar mass
193.2140g/mol
Density
1.2000g/cm3
Appearence

3-(4-Methoxyphenyl)prop-2-enehydroxamic acid is typically an off-white solid at room temperature.

Comment on solubility

Solubility of 3-(4-methoxyphenyl)prop-2-enehydroxamic acid

The solubility of 3-(4-methoxyphenyl)prop-2-enehydroxamic acid can be quite intriguing due to its structural components and functional groups. It is essential to consider various factors that affect solubility:

  • Polarity: This compound contains hydroxamic acid moieties, which are polar, suggesting that it is likely to exhibit good solubility in polar solvents such as water.
  • Hydrogen Bonding: The presence of hydroxyl groups enables the potential for hydrogen bonding, further enhancing solubility in aqueous environments.
  • Hydrophobic Interactions: The methoxy group, being hydrophobic, may limit solubility in non-polar solvents, emphasizing the importance of solvent choice.
  • pH Dependency: The solubility may vary with pH, as the ionization of the hydroxamic acid could affect its hydrophilicity.

In summary, while 3-(4-methoxyphenyl)prop-2-enehydroxamic acid is expected to be soluble in polar solvents due to its polar characteristics and capacity for hydrogen bonding, its solubility could be influenced by the nature of the solvent and the environmental pH. Understanding these factors is crucial for applications involving this compound.

Interesting facts

Interesting Facts about 3-(4-methoxyphenyl)prop-2-enehydroxamic acid

3-(4-methoxyphenyl)prop-2-enehydroxamic acid is a notable compound with a variety of interesting applications and properties that make it a subject of study in organic and pharmaceutical chemistry.

Key Highlights:

  • Functional Group Diversity: The presence of the hydroxamic acid functional group in this compound is particularly intriguing. Hydroxamic acids are derivatives of carboxylic acids and are known for their ability to form complexes with metal ions.
  • Pharmaceutical Relevance: Compounds containing hydroxamic acid structures have been investigated for their potential therapeutic effects. They often show promise as inhibitors of enzymes, specifically metalloproteinases, which play roles in various diseases.
  • Directional Synthesis: The synthesis of 3-(4-methoxyphenyl)prop-2-enehydroxamic acid typically involves key reactions like condensation followed by hydroxylation, which can provide insights into synthetic methods in organic chemistry.
  • Substituent Influence: The methoxy group attached to the aromatic ring enhances the compound’s electronic properties, influencing its reactivity and interactions in biological systems.
  • Research Opportunities: This compound offers avenues for further research, particularly in the exploration of its biological activities and potential modifications to enhance efficacy or reduce side effects.

As we delve deeper into the study of compounds like 3-(4-methoxyphenyl)prop-2-enehydroxamic acid, we uncover not just their chemical nature, but also their vital roles in advancing medicinal chemistry and our understanding of molecular interactions.

Synonyms
SCHEMBL14244673