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Meloxicam

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Identification
Molecular formula
C13H12N2O3
CAS number
71125-38-7
IUPAC name
3-[4-methyl-2-[(2-oxoindolin-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid
State
State

At room temperature, meloxicam is present as a solid substance. Its crystalline nature means it is typically found as a powder that may clump together under certain environmental conditions like humidity and higher temperature.

Melting point (Celsius)
255.00
Melting point (Kelvin)
528.00
Boiling point (Celsius)
600.00
Boiling point (Kelvin)
873.00
General information
Molecular weight
351.41g/mol
Molar mass
351.4050g/mol
Density
1.5000g/cm3
Appearence

Meloxicam appears as a yellow solid crystalline powder. It is practically insoluble in water, slightly soluble in methylene chloride, very slightly soluble in ethyl acetate, and soluble in a strong acid or base. The specific crystalline structure may vary depending on the form in which it is isolated or synthesized.

Comment on solubility

Solubility of 3-[4-methyl-2-[(2-oxoindolin-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid

The solubility of 3-[4-methyl-2-[(2-oxoindolin-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid (C13H12N2O3) can be influenced by various factors, largely due to the intricate structure of the compound. Here are some key points to consider:

  • Polarity: The compound contains polar functional groups which can contribute to its solubility in polar solvents like water.
  • Hydrogen Bonding: With potential for hydrogen bonding, particularly from the carboxylic acid group, this enhances solubility in polar media.
  • Solvent Type: It may exhibit limited solubility in non-polar solvents due to its polar nature, making it less favorable for hydrocarbon environments.
  • Temperature Effects: Generally, increased temperature can increase solubility, particularly for solid compounds, which should be tested accordingly.

The solubility profile is essential for understanding its behavior in biological systems and in various chemical processes. As emphasized in the field, "the solubility of a compound is a decisive factor in its reactivity and biological availability."

Overall, when assessing the solubility of this compound, it is crucial to experiment under various conditions to understand its practical applications fully.

Interesting facts

Interesting Facts about 3-[4-methyl-2-[(2-oxoindolin-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid

3-[4-methyl-2-[(2-oxoindolin-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid is a fascinating compound that falls under the category of bioactive molecules. Its structural complexity contributes to a variety of intriguing characteristics and potential applications in both medicinal chemistry and organic synthesis.

Key Points of Interest:

  • Bioactivity: This compound has demonstrated significant biological activities, making it a subject of interest for drug development and therapeutic research.
  • Structural Diversity: The unique combination of a pyrrole ring and an indoline moiety in its structure suggests potential for interactions with various biological targets, which may lead to the discovery of innovative treatments.
  • Synthetic Routes: The synthesis of 3-[4-methyl-2-[(2-oxoindolin-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid can be an excellent example for students of organic chemistry in exploring multi-step synthetic pathways.
  • Potential Applications: As a derivative of pyrrole, it is part of a rich class of compounds with properties that could be harnessed in developing new pharmaceuticals, particularly in combating diseases where traditional treatments have limitations.

In summary, 3-[4-methyl-2-[(2-oxoindolin-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid serves as more than just a chemical entity; it embodies the promise of modern medicinal chemistry with its potential therapeutic efficacy, making it a compound worth exploring for both seasoned scientists and curious students alike.

Synonyms
C17H16N2O3
CHEBI:63449
3-(4-methyl-2-{[(3Z)-2-oxo-1H-indol-3-ylidene]methyl}-1H-pyrrol-3-yl)propanoic acid
3-{4-METHYL-2-[(2-OXO-1H-INDOL-3-YLIDENE)METHYL]-1H-PYRROL-3-YL}PROPANOIC ACID
CHEMBL3188898
(Z)-3-(4-methyl-2-((2-oxoindolin-3-ylidene)methyl)-1H-pyrrol-3-yl)propanoic acid
HMS3244I03
HMS3244I04
HMS3244J03
BCP01961
s7667
AKOS030241811
NCGC00346878-01
3-[4-Methyl-2-(2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-1H-pyrrol-3-yl]-propionic acid
2-[(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-4-methyl-1H-pyrrole-3-propanoic acid 3-[3-(2-Carboxyethyl)-4-methylpyrrol-2-methylidenyl]-2-indolinone