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Cefpirome

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Identification
Molecular formula
C22H22N6O5S2
CAS number
84957-29-9
IUPAC name
3-[[4-(methylcarbamoyl)pyridin-1-ium-1-yl]methyl]-8-oxo-7-[[2-(2-thienyl)acetyl]amino]-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
State
State

Cefpirome is typically found in a solid crystalline form at room temperature. It may also come as a powder that is dissolved for injections or medications.

Melting point (Celsius)
212.00
Melting point (Kelvin)
485.15
Boiling point (Celsius)
355.40
Boiling point (Kelvin)
628.55
General information
Molecular weight
524.58g/mol
Molar mass
524.5600g/mol
Density
1.4803g/cm3
Appearence

Cefpirome is a white to pale yellow crystalline powder. It is an amphoteric compound which means it can react both as a base and as an acid. The compound can form hydrates and its appearance can change based on its purity and hydration level.

Comment on solubility

Solubility of 3-[[4-(methylcarbamoyl)pyridin-1-ium-1-yl]methyl]-8-oxo-7-[[2-(2-thienyl)acetyl]amino]-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

The solubility of this complex chemical compound is influenced by its unique structural characteristics and functional groups. Generally, solubility in solvents can be anticipated based on various factors:

  • Polarity: The presence of polar functional groups such as carboxylic acid and pyridine improves solubility in polar solvents like water.
  • Hydrogen Bonding: The ability to form hydrogen bonds due to the carboxylic acid functional group enhances interactions with polar solvents, which is crucial for solubility.
  • Hydrophobic Groups: The thienyl and carbamoyl moieties may introduce hydrophobic characteristics, potentially lowering solubility in highly polar solvents.
  • pH Sensitivity: The acidic and basic nature of certain groups suggests that solubility could vary significantly with changes in pH; typically, the ionization of acidic groups can increase solubility in alkaline conditions.

In summary, it can be said that solubility is largely dependent on intermolecular interactions and the overall balance of hydrophilic and hydrophobic regions within the molecule. For practical applications, it is essential to conduct solubility tests in various solvents to determine the most favorable conditions for this 3-[[4-(methylcarbamoyl)pyridin-1-ium-1-yl]methyl]-8-oxo-7-[[2-(2-thienyl)acetyl]amino]-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid. Knowing the solubility profile can assist in further compound applications in pharmacology and material sciences.

Interesting facts

Interesting Facts About 3-[[4-(methylcarbamoyl)pyridin-1-ium-1-yl]methyl]-8-oxo-7-[[2-(2-thienyl)acetyl]amino]-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

This compound is an intriguing member of the bicyclic organic compounds, notable for its complex structure and potential applications in medicinal chemistry. Here are several key points to consider:

  • Diverse Functional Groups: The presence of both a methylcarbamoyl and thienyl group contributes to the compound's unique chemical properties, showcasing the versatility of organic synthesis.
  • Potential Biological Activity: Compounds with similar structural characteristics have been investigated for their pharmacological effects, including anti-inflammatory and anti-cancer properties. As a result, this compound could be a candidate for future drug development.
  • Role as a Building Block: The bicyclic structure serves as an excellent scaffold for the development of new compounds. Scientists often utilize such moieties to explore their interaction with biological targets.
  • Research Opportunities: Given the complex nature of this compound, it presents multiple avenues for research, from studying its synthesis pathways to evaluating its efficiency in biological assays.
  • Interdisciplinary Connections: The study of this compound spans various fields, including organic chemistry, pharmacology, and materials science, making it an exciting topic for collaborative research.

In conclusion, 3-[[4-(methylcarbamoyl)pyridin-1-ium-1-yl]methyl]-8-oxo-7-[[2-(2-thienyl)acetyl]amino]-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid exemplifies the beauty of organic chemistry through its intricate design and potential benefits. As researchers continue to unravel its properties, we can anticipate further advancements in its applications.

Synonyms
3-[[4-(methylcarbamoyl)pyridin-1-ium-1-yl]methyl]-8-oxo-7-[(2-thiophen-2-ylacetyl)amino]-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
5182-52-5
DTXSID90274697