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Meloxicam

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Identification
Molecular formula
C14H13N3O4S2
CAS number
71125-38-7
IUPAC name
3-[(4-methylisothiazol-5-yl)methyleneamino]isothiourea
State
State

At room temperature, meloxicam is typically in a solid state. It is used in oral tablet and suspension forms for medical applications.

Melting point (Celsius)
255.00
Melting point (Kelvin)
528.20
Boiling point (Celsius)
591.50
Boiling point (Kelvin)
864.70
General information
Molecular weight
318.36g/mol
Molar mass
318.3630g/mol
Density
1.5180g/cm3
Appearence

Meloxicam typically appears as a yellow solid in various forms such as powder or crystals. It is relatively stable and used in pharmaceutical applications.

Comment on solubility

Solubility of 3-[(4-methylisothiazol-5-yl)methyleneamino]isothiourea

The solubility of 3-[(4-methylisothiazol-5-yl)methyleneamino]isothiourea can be quite intriguing, as it showcases the behavior of isothioureas in different solvents. The compound is expected to exhibit the following solubility characteristics:

  • Water Solubility: Generally, isothioureas may exhibit moderate water solubility due to the presence of polar groups.
  • Organic Solvents: This compound may be more soluble in organic solvents, particularly those with similar polarities, enhancing its dissolution.
  • Temperature Effects: Solubility can increase with temperature; thus, assessing solubility at various temperatures is essential.

In considering the overall solubility of this compound, it is important to recognize the molecular structure and interactions at play. Hydrogen bonding, as well as other intermolecular forces, significantly influence solubility. As is often the case with similar compounds, the solubility can vary based on:

  • pH of the solution
  • Presence of co-solvents
  • Concentration of the compound

Overall, understanding the solubility of 3-[(4-methylisothiazol-5-yl)methyleneamino]isothiourea is fundamental for its practical application in various fields, particularly in biological systems where effective absorption and interaction are key.

Interesting facts

Interesting Facts about 3-[(4-methylisothiazol-5-yl)methyleneamino]isothiourea

This compound, with a unique molecular structure, belongs to a fascinating class of chemicals known as isothioureas. Isothioureas have drawn attention in various areas of research, especially due to their biological activities and potential applications.

Biological Significance

  • Antimicrobial Properties: Compounds in the isothiourea family often exhibit strong antimicrobial properties, making them valuable in the field of biochemistry.
  • Enzyme Inhibition: Some isothioureas can act as enzyme inhibitors, influencing metabolic pathways which can be crucial in therapeutic contexts.
  • Cancer Research: The unique chemical structure of isothioureas like this compound lends itself to exploration in cancer research, where they may interact with specific cellular targets.

Chemical Structure and Reactivity

The presence of a methyl group within the isothiazole ring enhances the compound's chemical reactivity and bioactivity. This highlights the importance of subtle structural modifications in the behavior of chemical compounds:

  • Resonance Structures: The arrangement of electrons in the compound allows for resonance stabilization, which can influence its reactivity.
  • Intermolecular Interactions: The nitrogen and sulfur atoms within its structure are capable of forming hydrogen bonds, potentially influencing solubility and interaction with other biological molecules.

Application Potential

This compound isn't just a laboratory curiosity but has practical implications, as seen in:

  • Development of antifungal agents due to its ability to disrupt microbial growth.
  • Research into agricultural biocontrol agents, where compounds like this can be used to protect crops.
  • Investigation of potential therapeutics targeting specific diseases, showcasing the promise of smart design in medicinal chemistry.

In conclusion, 3-[(4-methylisothiazol-5-yl)methyleneamino]isothiourea stands out for its diverse applications and biological significance, exemplifying the intricate relationships between chemical structure and biological activity. Its study not only enriches our understanding of isothioureas but may also pave the way for novel solutions in health and agriculture. The field of chemistry continues to reveal the profound impact that these compounds can have on society.