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4-Nitrochalcone

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Identification
Molecular formula
C15H11NO3
CAS number
605-96-7
IUPAC name
3-(4-nitrophenyl)-1-phenyl-prop-2-en-1-one
State
State

At room temperature, 4-Nitrochalcone exists as a solid, specifically in the form of crystalline powder. This solid state is typical for many organic compounds, particularly those with aromatic rings and conjugated systems.

Melting point (Celsius)
156.00
Melting point (Kelvin)
429.00
Boiling point (Celsius)
424.00
Boiling point (Kelvin)
697.00
General information
Molecular weight
269.26g/mol
Molar mass
269.2670g/mol
Density
1.3000g/cm3
Appearence

4-Nitrochalcone is a crystalline solid that can range in color from yellow to orange. Its appearance is typically described as having a lustrous surface, which is often typical of organic crystalline materials. The intensity of the color can depend on the purity of the sample.

Comment on solubility

Solubility of 3-(4-nitrophenyl)-1-phenyl-prop-2-en-1-one

The solubility of 3-(4-nitrophenyl)-1-phenyl-prop-2-en-1-one, commonly referred to as a nitrophenyl derivative, can be influenced by several factors, primarily its molecular structure and the nature of the solvent. Here are some key points regarding its solubility:

  • Polarity: This compound exhibits a balance between polar and nonpolar characteristics, which affects its interaction with solvents. Generally, compounds with significant aromatic rings tend to have lower solubility in polar solvents.
  • Solvent Type: It is usually more soluble in organic solvents such as ethanol, methanol, and dichloromethane compared to water. This non-polar tendency is attributed to the extensive conjugated system in its structure.
  • Temperature Influence: Solubility often increases with temperature; hence, dissolving the compound at elevated temperatures may enhance its solubility even in less favorable solvents.
  • pH Sensitivity: The presence of the nitro group can lead to variations in solubility under different pH conditions, as protonation and deprotonation can alter the compound’s solubility characteristics.

In summary, the solubility of 3-(4-nitrophenyl)-1-phenyl-prop-2-en-1-one is largely governed by its structural features and the chemistry of the solvent used. As always, experimental solubility studies are recommended to determine precise solubility limits in any given scenario.

Interesting facts

Interesting Facts about 3-(4-Nitrophenyl)-1-phenyl-prop-2-en-1-one

3-(4-Nitrophenyl)-1-phenyl-prop-2-en-1-one, often referred to as a type of chalcone, is a fascinating organic compound that showcases the intersection of chemistry and biology. Here are some intriguing aspects of this compound:

  • Structural Characteristics: Being a chalcone, it features a significant α,β-unsaturated carbonyl system. This unique structure is crucial for its chemical reactivity and biological activity.
  • Applications in Research: This compound is often studied for its potential antioxidant and antimicrobial properties, making it a candidate for pharmaceutical research.
  • Biological Significance: Some studies suggest that chalcones can exhibit anti-inflammatory and anticancer activities, indicating the potential for medicinal applications.
  • Synthetic Pathways: The synthesis of chalcones, including this compound, usually involves the Claisen-Schmidt reaction, where an aldehyde reacts with a ketone in the presence of a base.
  • Unique Substituent Effects: The presence of the nitrophenyl group in this structure enhances the compound's electron-withdrawing ability, significantly influencing its reactivity and potential biological effects.

As a chemistry student or a researcher, understanding such compounds can pave the way to innovative solutions in drug design and materials science. The study of 3-(4-Nitrophenyl)-1-phenyl-prop-2-en-1-one is a prime example of how detailed explorations in organic chemistry can lead to impactful discoveries.

Synonyms
3-(4-nitrophenyl)-1-phenylprop-2-en-1-one
MFCD00007382
4-nitrobenzalacetophenone
DTXSID50859601
WDZGGAFMGIOIQS-UHFFFAOYSA-N
2-(4-Nitrobenzylidene)acetophenone
AKOS004905415
3-(4-Nitro-phenyl)-1-phenyl-propenone
SY040613
DB-041659
N0839
D95246
3-(4-nitro-phenyl)-1-phenyl-prop-2-en-1-one