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3-(4-nitrophenyl)azetidine

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Identification
Molecular formula
C9H10N2O2
CAS number
31431-19-7
IUPAC name
3-(4-nitrophenyl)azetidine
State
State

At room temperature, 3-(4-nitrophenyl)azetidine is in a solid state, usually found as a powder or crystalline form.

Melting point (Celsius)
88.00
Melting point (Kelvin)
361.15
Boiling point (Celsius)
312.00
Boiling point (Kelvin)
585.15
General information
Molecular weight
178.19g/mol
Molar mass
178.1880g/mol
Density
1.3000g/cm3
Appearence

3-(4-nitrophenyl)azetidine is typically a solid compound that may appear as a colored powder or crystalline substance due to the presence of the nitrophenyl group, which often imparts a yellowish hue.

Comment on solubility

Solubility of 3-(4-nitrophenyl)azetidine

3-(4-nitrophenyl)azetidine, a compound characterized by its unique azetidine structure with a nitrophenyl substituent, presents interesting traits when it comes to solubility. The solubility of this compound can be influenced by several factors:

  • Polarity: Due to the presence of the nitro group (–NO2), which is highly polar, 3-(4-nitrophenyl)azetidine is likely to exhibit increased water solubility compared to non-polar compounds.
  • Solvent Properties: It is expected to be soluble in polar solvents such as ethanol and dimethyl sulfoxide (DMSO), but might have limited solubility in non-polar organic solvents.
  • Hydrogen Bonding: The potential for hydrogen bonding with water molecules enhances the solubility of this compound, especially given the possible interactions of the azetidine nitrogen.

In summary, while 3-(4-nitrophenyl)azetidine demonstrates some solubility in polar environments, its solubility behavior can vary considerably based on the medium. As a result, understanding the solubility characteristics is essential for applications in pharmaceuticals and material science, where solubility plays a pivotal role in drug formulation and compound behavior.

Interesting facts

Interesting Facts about 3-(4-nitrophenyl)azetidine

3-(4-nitrophenyl)azetidine is a fascinating compound that combines the unique properties of azetidine with the electronegative effects of a nitrophenyl group. Here are some engaging insights into this intriguing molecule:

  • Structural Diversity: Azetidine is a four-membered saturated heterocyclic compound. The incorporation of the 4-nitrophenyl group introduces structural diversity and can influence the reactivity and properties of the compound.
  • Biological Relevance: Compounds similar to 3-(4-nitrophenyl)azetidine are often studied for their biological activities. They may exhibit antimicrobial, antifungal, or antitumor properties, making them of interest in medicinal chemistry.
  • Electron-Withdrawing Effects: The nitro group (-NO2) is a strong electron-withdrawing substituent. This can significantly affect the overall electron density on the azetidine ring, leading to potential interactions in chemical reactions.
  • Synthetic Applications: The azetidine ring system serves as a valuable scaffold in organic synthesis, making it a target for synthetic chemists. The functionalization of this ring can lead to the development of novel materials and compounds.
  • Research Potential: Due to its unique structural features, 3-(4-nitrophenyl)azetidine is a potential candidate for further studies in the fields of drug discovery and materials science.

In summary, 3-(4-nitrophenyl)azetidine is not just a compound; it’s a gateway to exploring the interplay between structure and function in chemistry. Its potential applications and remarkable properties continue to inspire research and innovation.

Synonyms
7215-05-6
3-(p-Nitrophenyl)azetidine
AZETIDINE, 3-(p-NITROPHENYL)-
L 2407
BRN 1428021
DTXSID70222474
DTXCID70144965
5-20-06-00286 (beilstein handbook reference)
3-(4-nitrophenyl)azetidine
GS0573
MFCD01665441
SY279694
EN300-1828704