3-(4-propoxyphenyl)prop-2-enehydroxamic acid

Identification

Molecular formula

C₁₂H₁₅NO₃

CAS number

IUPAC name

3-(4-propoxyphenyl)prop-2-enehydroxamic acid

State

At room temperature, 3-(4-propoxyphenyl)prop-2-enehydroxamic acid is typically found as a solid due to its crystalline nature.

Melting point (Celsius)

129.00

Melting point (Kelvin)

402.00

Boiling point (Celsius)

398.00

Boiling point (Kelvin)

671.00

General information

Molecular weight

221.27g/mol

Molar mass

221.2690g/mol

Density

1.1450g/cm³

Appearence

3-(4-propoxyphenyl)prop-2-enehydroxamic acid is typically a crystalline solid. The appearance can vary based on the form and purity of the sample. It can appear as white to light tan crystals or powder.

Comment on solubility

Solubility of 3-(4-propoxyphenyl)prop-2-enehydroxamic acid

3-(4-propoxyphenyl)prop-2-enehydroxamic acid is an intriguing compound when it comes to solubility. Several factors influence the solubility of this compound in various solvents:

Polarity: The presence of the hydroxamic acid functional group generally enhances solubility in polar solvents such as water.
Hydrophobic tails: The propoxy group tends to contribute hydrophobic character, which can decrease solubility in highly polar solvents but may promote solubility in organic solvents.
Hydrogen bonding: The ability to form hydrogen bonds with solvent molecules greatly influences solubility, particularly in polar solvents.

As a result, this compound may exhibit:

Good solubility in: Alcohols, where the polar hydroxamic group can interact favorably.
Limited solubility in: Non-polar solvents, due to the presence of polar groups competing for solvation.

Furthermore, it's essential to note that temperature and pH of the solution can also have significant effects on solubility. In practice, it may be observed that solubility variations occur depending on the specific conditions applied during experiments. Hence, careful evaluation of solvent conditions is critical when working with 3-(4-propoxyphenyl)prop-2-enehydroxamic acid.

Interesting facts

Interesting Facts about 3-(4-propoxyphenyl)prop-2-enehydroxamic acid

3-(4-propoxyphenyl)prop-2-enehydroxamic acid is a fascinating compound that bridges organic chemistry and bioactivity. Known for its potential applications in medicinal chemistry, this compound offers a unique structure that allows it to engage in various biochemical interactions.

Pharmacological Potential: This compound is being studied for its ability to inhibit specific enzymes, making it a candidate for developing therapeutic agents against certain diseases.
Hydroxamic Acid Motif: The presence of the hydroxamic acid functional group is noteworthy, as it is often associated with the inhibition of metalloproteinases, which play critical roles in cancer progression and tissue remodeling.
Synthetic Versatility: The structural design of 3-(4-propoxyphenyl)prop-2-enehydroxamic acid allows for various synthetic modifications. This means it can be tailored to enhance its activity or selectivity, opening pathways for novel drug discovery.
Combinatorial Chemistry: This compound exemplifies the use of combinatorial chemistry techniques, where multiple variations can be rapidly synthesized and screened for biological activity, significantly speeding up the drug development process.

Moreover, the propoxyphenyl group introduces interesting electronic and steric properties that may influence the compound's reactivity and interaction with biological targets. In the words of chemist and researcher, "Each modification can potentially breathe new life into the compound's utility."

As research continues, understanding the dynamics and mechanisms of 3-(4-propoxyphenyl)prop-2-enehydroxamic acid may pave the way for innovative treatments and deepen our knowledge of how chemical compounds can be utilized in fighting disease.