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Xylometazoline

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Identification
Molecular formula
C16H20N2
CAS number
526-36-3
IUPAC name
3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-1H-indole
State
State
Xylometazoline is a solid at room temperature.
Melting point (Celsius)
139.00
Melting point (Kelvin)
412.15
Boiling point (Celsius)
411.80
Boiling point (Kelvin)
684.95
General information
Molecular weight
244.35g/mol
Molar mass
244.3180g/mol
Density
1.0875g/cm3
Appearence

Xylometazoline typically appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-1H-indole

The solubility of 3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-1H-indole can vary significantly based on several factors including temperature, pH, and the solvent used. Here are some key points to consider:

  • Polarity of the solvent: As a general rule, compounds tend to be more soluble in solvents that have similar polarity. This compound, with its complex structure, may exhibit varying solubility in polar versus non-polar solvents.
  • Temperature dependence: Increasing temperature often enhances the solubility of organic compounds, therefore it is essential to conduct solubility assessments at different temperatures for accurate data.
  • pH effect: Given the presence of potential acidic or basic sites in the compound’s structure, the pH of the solution can affect the ionization of the molecule, influencing its overall solubility.
  • Concentration of stock solutions: When preparing for experiments or applications, understanding how concentration affects solubility can aid in maximizing effectiveness.

In conclusion, the solubility of 3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-1H-indole is influenced by various factors that must be carefully controlled and considered during experimentation and application. As such, conducting systematic solubility studies under different conditions is critical for its research and potential uses.

Interesting facts

Interesting Facts about 3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-1H-indole

3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-1H-indole is a fascinating compound that blends the characteristics of both indole and imidazole moieties, which are known for their significant roles in biological systems and medicinal chemistry. Here are some intriguing insights into this compound:

  • Biological Relevance: Indole derivatives are widely studied for their biological activities, including their potential as antidepressants and anti-inflammatory agents. This specific compound combines indole with an imidazole group, which is often found in pharmacologically active molecules.
  • Modulatory Roles: Compounds like this one can serve as modulators for various biochemical pathways. The imidazole ring is a versatile motif seen in many drug structures, making it a target of interest in drug design.
  • Versatile Chemistry: The incorporation of a dihydro-imidazole structure may impart unique electronic properties, affecting the compound's reactivity and interaction with biological targets.
  • Potential Applications: Researchers are exploring the use of indole and imidazole derivatives in the development of new therapeutic agents. Compounds resembling 3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-1H-indole might present opportunities in areas such as oncology or neurology.
  • Synthetic Challenges: The synthesis of such complex organic compounds often involves multiple steps, including condensation reactions and functional group transformations, paving the way for rigorous exploration in synthetic organic chemistry.

In summary, 3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-1H-indole presents a rich area for scientific exploration, given its structural features and potential biological activity. As chemists continue to assess and experiment with this compound, it may lead to groundbreaking discoveries in both pharmacology and organic synthesis.

Synonyms
19853-01-1
BRN 0173110
1H-INDOLE, 3-(2-IMIDAZOLIN-2-YLMETHYL)-
3-(2-Imidazolin-2-ylmethyl)1H-indole
2-(Indolyl-(3')-methyl)imidazolin [German]
2-(Indolyl-(3')-methyl)imidazolin
DTXSID60173603
4-26-00-00196 (Beilstein Handbook Reference)
DTXCID7096094
RefChem:238784
SCHEMBL956475