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Erlotinib

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Identification
Molecular formula
C22H23ClN2O4
CAS number
183319-69-9
IUPAC name
3-[5-chloro-2-(2-morpholinoethoxy)phenyl]-1-(2-methoxyphenyl)prop-2-en-1-one
State
State

At room temperature, Erlotinib is typically found as a solid.

Melting point (Celsius)
223.00
Melting point (Kelvin)
496.15
Boiling point (Celsius)
524.60
Boiling point (Kelvin)
797.80
General information
Molecular weight
393.88g/mol
Molar mass
393.8250g/mol
Density
1.4494g/cm3
Appearence

Erlotinib is typically an off-white to yellow solid.

Comment on solubility

Solubility of 3-[5-chloro-2-(2-morpholinoethoxy)phenyl]-1-(2-methoxyphenyl)prop-2-en-1-one

The solubility of 3-[5-chloro-2-(2-morpholinoethoxy)phenyl]-1-(2-methoxyphenyl)prop-2-en-1-one can be an intriguing factor in its application and reactivity. Understanding its solubility behavior is essential for effective utilization in various fields, particularly in pharmaceuticals where bioavailability is a crucial aspect. Here are some important considerations regarding its solubility:

  • Polar vs. Non-Polar Solvents: Typically, compounds with significant aromatic character, such as this one, may exhibit greater solubility in organic solvents (e.g., ethanol, dimethyl sulfoxide (DMSO)) compared to polar solvents like water.
  • Effect of Substituents: The presence of functional groups such as -OCH₃ and -Cl can enhance solubility in certain solvents while potentially reducing solubility in others due to steric hindrance or electronic effects.
  • Temperature Influence: Like many organic compounds, solubility can increase with temperature, making it crucial to consider this factor during experiments.
  • Concentration Threshold: Careful consideration of saturation levels is necessary to avoid precipitate formation in solutions, which can complicate reactions and analyses.

In summary, the solubility of this compound is influenced by its structural components and the choice of solvent. While it may exhibit solubility in various organic solvents, the exact conditions need to be optimized for specific applications. As we explore further, the intricate balance between solubility and stability will unveil new avenues for research and application.

Interesting facts

Interesting Facts about 3-[5-chloro-2-(2-morpholinoethoxy)phenyl]-1-(2-methoxyphenyl)prop-2-en-1-one

This compound is a fascinating example of a synthetic organic molecule with significant implications in medicinal chemistry. Here are some noteworthy points about this compound:

  • Structure and Functionality: The intricate molecular structure features multiple aromatic rings and functional groups that contribute to its unique properties. The presence of a chloro group and a morpholinoethoxy group enhances its potential reactivity and biological activity.
  • Potential Biological Activity: Compounds of this nature are often studied for their pharmacological properties, such as anti-inflammatory and anticancer activities. The molecular design suggests it may interact favorably with biological targets.
  • Synthetic Versatility: This compound can be synthesized using various organic reactions, which allows for the development of derivatives that may possess improved efficacy or reduced toxicity.
  • Medicinal Applications: Given its structural characteristics, researchers are exploring its use in developing new therapeutic agents. Molecules that resemble this compound have shown promise in clinical studies for various diseases.
  • Mechanisms of Action: As with many compounds, investigating the mechanism by which this molecule exerts its effects can lead to insights into how to optimize its therapeutic potential. Understanding binding interactions with enzymes or receptors is crucial.

In conclusion, the compound 3-[5-chloro-2-(2-morpholinoethoxy)phenyl]-1-(2-methoxyphenyl)prop-2-en-1-one represents the intersection of chemistry and pharmacology, offering exciting prospects for innovation in drug development. Its complex architecture not only makes it an interesting subject for study but also surfaces possibilities for improving health outcomes in disease treatment.