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Clomipramine

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Identification
Molecular formula
C19H23ClN2
CAS number
303-49-1
IUPAC name
3-(5-chloro-2-tricyclo[9.4.0.03,8]pentadeca-1(15),3(8),4,6,11,13-hexaenylidene)-N,N-dimethyl-propan-1-amine
State
State
At room temperature, clomipramine is typically solid, presented as a powder that is commonly used in the preparation of pharmaceutical tablets or capsules.
Melting point (Celsius)
192.00
Melting point (Kelvin)
465.15
Boiling point (Celsius)
402.00
Boiling point (Kelvin)
675.15
General information
Molecular weight
314.86g/mol
Molar mass
314.8910g/mol
Density
0.8525g/cm3
Appearence
Clomipramine appears as a white to off-white crystalline powder. It is usually found in a powder form suitable for forming tablets or capsules.
Comment on solubility

Solubility of 3-(5-chloro-2-tricyclo[9.4.0.03,8]pentadeca-1(15),3(8),4,6,11,13-hexaenylidene)-N,N-dimethyl-propan-1-amine

The solubility of 3-(5-chloro-2-tricyclo[9.4.0.03,8]pentadeca-1(15),3(8),4,6,11,13-hexaenylidene)-N,N-dimethyl-propan-1-amine is a complex topic due to its unique structure. Similar to many organic compounds, its solubility can be affected by various factors, including:

  • Molecular Structure: The presence of tricyclic and aromatic regions often influences its ability to interact with solvents.
  • Functional Groups: The amine group (–N,N-dimethyl) can impart basic properties, potentially enhancing solubility in acidic media.
  • Polarity: The overall polarity of the compound dictates its solubility in polar versus non-polar solvents.

Generally, compounds similar to this structure may display:

  • Poor solubility in water: Due to hydrophobic characteristics from its extensive hydrocarbon framework.
  • Enhanced solubility in organic solvents: Such as dichloromethane or ethanol, which can better accommodate large, non-polar structures.

In practice, one could state that the solubility of this compound exemplifies a classic trade-off between molecular complexity and solvent interaction capabilities. As with many such high-functionality molecules, *"the key is to experiment and characterize solubility under specific conditions."* This might reveal intriguing potential for applications in various fields such as medicinal chemistry and materials science.

Interesting facts

Exploring 3-(5-Chloro-2-tricyclo[9.4.0.03,8]pentadeca-1(15),3(8),4,6,11,13-hexaenylidene)-N,N-dimethyl-propan-1-amine

This fascinating compound belongs to a class of chemicals known for their intricate structures and potential applications in medicinal chemistry and organic synthesis. Here are some intriguing facts:

  • Complex Structure: The name itself reveals a challenging molecular architecture, showcasing the presence of multiple cycloalkanes—the tricyclic structure adds significant stability and uniqueness to its interaction properties.
  • Bioactivity Potential: Compounds with such elaborate scaffolds are often explored for biological activity. Research indicates that structural complexity may relate to enhanced binding affinity to biological targets, thus opening doors for drug design.
  • Chlorine’s Role: The incorporation of chlorine in the compound can alter its biological activity. Chlorinated compounds frequently demonstrate unique chemical properties, making them of interest in the field of pharmaceuticals.
  • Dimethylamino Group: The presence of the N,N-dimethylamino functionality can enhance solubility in biological systems and provide electron-donating properties, influencing reactivity.
  • Synthesis Challenges: The synthesis of such complex molecules can be a Herculean task in organic chemistry, requiring advanced techniques and creativity from chemists.

As a result, 3-(5-chloro-2-tricyclo[9.4.0.03,8]pentadeca-1(15),3(8),4,6,11,13-hexaenylidene)-N,N-dimethyl-propan-1-amine captures the interest of scientists not just for its potential applications, but also for the intriguing challenges it presents in synthesis and characterization.

In the words of famed chemist Linus Pauling, "The best way to have a good idea is to have a lot of ideas." Exploring compounds like this one can lead to unexpected innovations in chemical research.