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Methantheline

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Identification
Molecular formula
C21H30N2O2Cl2
CAS number
80-48-8
IUPAC name
[3-[[5-[(dimethylammonio)methyl]-2-methoxy-phenyl]methyl]-4-methoxy-phenyl]methyl-dimethyl-ammonium;dichloride
State
State

At room temperature, Methantheline dichloride is in a solid state, generally in the form of a powder. It is stable under normal conditions of temperature and pressure.

Melting point (Celsius)
132.00
Melting point (Kelvin)
405.15
Boiling point (Celsius)
180.00
Boiling point (Kelvin)
453.15
General information
Molecular weight
418.49g/mol
Molar mass
418.4900g/mol
Density
1.0507g/cm3
Appearence

Methantheline, in its dichloride form, typically appears as a white or off-white crystalline powder. It is hygroscopic and may absorb moisture from the air. Its crystalline nature gives it a slightly glossy appearance under light. The compound is typically odorless and tasteless.

Comment on solubility

Solubility of 3-[[5-[(dimethylammonio)methyl]-2-methoxy-phenyl]methyl]-4-methoxy-phenyl]methyl-dimethyl-ammonium dichloride

This compound exhibits a unique solubility profile characteristic of quaternary ammonium salts. Solubility can be influenced by several factors:

  • Polarity: The presence of multiple methoxy groups increases the polarity of the molecule, enhancing its solubility in polar solvents such as water.
  • Ionization: As a quaternary ammonium salt, it is likely to ionize in aqueous solution, further aiding in its solubility through interactions with water molecules.
  • Concentration: At higher concentrations, the solubility may reach saturation, beyond which precipitates could form.
  • Temperature: Increased temperature generally increases solubility of solids in liquids, which may benefit this compound.

In contrast, it may show lower solubility in non-polar solvents due to the absence of suitable interactions. As a general rule, like dissolves like; hence, this compound is more likely to dissolve in organic solvents that can interact favorably with its structures, such as dimethyl sulfoxide (DMSO) or acetone.

Due to its ionic and polar characteristics, this compound's solubility behavior is critical for its applications, influencing aspects such as stability, transport, and biological activity.

Interesting facts

Interesting Facts about 3-[[5-[(dimethylammonio)methyl]-2-methoxy-phenyl]methyl]-4-methoxy-phenyl]methyl-dimethyl-ammonium;dichloride

This compound, belonging to the class of quaternary ammonium salts, highlights the fascinating interplay of organic chemistry and pharmacology. Known for its unique structure and properties, it serves multiple roles in both industrial and research settings.

1. Diverse Applications

  • Antibiotic Activity: Many compounds of this class exhibit antimicrobial properties, making them valuable in pharmaceutical formulations.
  • Surface-active Agent: Its ability to reduce surface tension has made it useful in formulations such as disinfectants and antiseptics.

2. Structural Significance

The compound features a complex arrangement with multiple methoxy groups and dimethylammonio substituents. This structural diversity enhances its interaction with biological systems, exemplifying how slight alterations in chemical structure can lead to dramatic changes in function.

3. Promising Research Pathways

  • Drug Development: Researchers are investigating the modification of this compound to improve matrix stability for drug delivery.
  • Material Science: Its unique properties make it a candidate for creating novel materials, potentially evolving the field of nanotechnology.

In conclusion, 3-[[5-[(dimethylammonio)methyl]-2-methoxy-phenyl]methyl]-4-methoxy-phenyl]methyl-dimethyl-ammonium;dichloride stands as a testament to the intricate world of synthetic chemistry. Its multifunctionality and structural complexity not only engage the interest of chemists but also inspire innovations across various scientific domains. As noted by chemists, "The beauty of organic chemistry lies in our ability to transform simple molecules into complex constructs with remarkable properties."

Synonyms
Bis-(5-dimethylaminomethyl-2-methoxyphenyl)methane dihydrochloride
BENZYLAMINE, 3,3'-METHYLENEBIS(N,N-DIMETHYL-4-METHOXY-, DIHYDROCHLORIDE
5820-00-8