Skip to main content

Thioflavine T

ADVERTISEMENT
Identification
Molecular formula
C15H10O4
CAS number
2390-54-7
IUPAC name
3-(5-hydroxy-3-oxo-4-phenyl-2-furylidene)benzofuran-2-one
State
State

At room temperature, the compound is in a solid state. It does not readily dissolve in water but may dissolve in organic solvents, which is often used to utilize its fluorescent properties.

Melting point (Celsius)
276.00
Melting point (Kelvin)
549.15
Boiling point (Celsius)
347.00
Boiling point (Kelvin)
620.15
General information
Molecular weight
169.15g/mol
Molar mass
169.1470g/mol
Density
1.4747g/cm3
Appearence

The compound appears as a yellow crystal powder. It is typically crystalline in nature and is yellow in coloration, having characteristic fluorescence properties. The powder is often used in various applications due to its bright appearance.

Comment on solubility

Solubility of 3-(5-hydroxy-3-oxo-4-phenyl-2-furylidene)benzofuran-2-one

The compound 3-(5-hydroxy-3-oxo-4-phenyl-2-furylidene)benzofuran-2-one, with the chemical formula C15H10O4, exhibits some interesting solubility characteristics that are worth noting. Understanding the solubility of a compound is crucial as it influences its application in various fields such as pharmaceuticals, chemical synthesis, and material science.

Solubility Characteristics:

  • Solvent Interaction: This compound tends to dissolve better in organic solvents, particularly those with moderate polarity, due to its aromatic and furan rings.
  • Polarity Consideration: The presence of multiple functional groups such as hydroxy (-OH) and carbonyl (C=O) may enhance its interaction with polar solvents, albeit its overall structure suggests limited solubility in highly polar solvents like water.
  • Solubility Temperature Dependency: Like many organic compounds, its solubility may increase with temperature, allowing for a better dissolution in hot solvents.
  • Dissolution Rate: The dissolution rate may vary depending on the particle size, crystal form, and method of dispersion, which can further impact its applications.

In summary, while the solubility of 3-(5-hydroxy-3-oxo-4-phenyl-2-furylidene)benzofuran-2-one can be somewhat complex, it primarily favors organic solvents. Factors such as temperature and solvent choice are vital in achieving optimal solubility. As always, the specific conditions and experimental setup will dictate the actual solubility experienced in practical applications.

Interesting facts

Exploring 3-(5-hydroxy-3-oxo-4-phenyl-2-furylidene)benzofuran-2-one

This fascinating compound, known as 3-(5-hydroxy-3-oxo-4-phenyl-2-furylidene)benzofuran-2-one, belongs to the class of benzofuran derivatives and has attracted attention due to its unique structural features and potential applications.

Key Features and Properties

  • Structural Diversity: The compound's structure includes both a benzofuran and a furan moiety, providing a rich framework for chemical reactivity and interaction with biological systems.
  • Bioactivity: Compounds of this nature are often studied for their therapeutic potential. They may possess antioxidant, anti-inflammatory, and antimicrobial properties, making them candidates for pharmaceutical research.
  • Research Applications: Scientists are investigating how modifications to this molecular framework can enhance its efficacy or selectivity in biological assays.
  • Synthesis: Developing synthetic routes for such compounds is of great interest, especially regarding their reactivity and the formation of complex structures that arise from interactions within the furan and carbonyl functionalities.

Notable Studies

Recent studies have highlighted the compound's potential in various fields:

  • Investigating its role as a lead compound for novel drug designs.
  • Examining its utility as a fluorescent probe in biological imaging.
  • Assessing its interactions with metal ions for applications in coordination chemistry.

In conclusion, 3-(5-hydroxy-3-oxo-4-phenyl-2-furylidene)benzofuran-2-one exemplifies the intricate relationship between structure and biological activity. Each study not only expands our understanding of this compound but also opens new pathways in medicinal chemistry and material science.