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Nifuroxazide

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Identification
Molecular formula
C7H5NO5
CAS number
965-52-6
IUPAC name
3-(5-nitro-2-furyl)prop-2-enoic acid
State
State

This compound is typically found in a solid state at room temperature as it is a crystalline powder. Its solid state along with its stability makes it useful for oral antibiotics administration in its solid formulation.

Melting point (Celsius)
197.00
Melting point (Kelvin)
470.15
Boiling point (Celsius)
385.00
Boiling point (Kelvin)
658.15
General information
Molecular weight
196.15g/mol
Molar mass
196.1450g/mol
Density
1.4608g/cm3
Appearence

Nifuroxazide appears as a yellow crystalline powder. It is typically odorless and has a slightly bitter taste. The powder form provides it excellent solubility in various solvents, with a unique color that is often indicative of compounds containing nitro groups.

Comment on solubility

Solubility of 3-(5-nitro-2-furyl)prop-2-enoic acid

The solubility of 3-(5-nitro-2-furyl)prop-2-enoic acid can be influenced by various factors, including its molecular structure and the nature of the solvent. Generally, the presence of the nitro group and the furan ring can affect its solubility characteristics. Here are some important points to consider:

  • Polar vs. Non-Polar Solvents: Compounds like 3-(5-nitro-2-furyl)prop-2-enoic acid, which contain polar functional groups (like carboxylic acids), tend to be more soluble in polar solvents such as water and alcohols.
  • Hydrogen Bonding: The ability to form hydrogen bonds with solvent molecules can enhance solubility. The carboxylic acid group in this molecule may engage in hydrogen bonding, thus increasing solubility in polar environments.
  • Temperature Effects: Solubility typically increases with temperature; thus, heating the solvent might increase the dissolution of this compound.
  • pH Influence: The solubility of acidic compounds can be significantly impacted by pH; for instance, under basic conditions, the carboxylic acid group may deprotonate, leading to increased solubility.

In summary, the solubility of 3-(5-nitro-2-furyl)prop-2-enoic acid is an intricate interplay of its chemical structure and the interaction with the solvent. As a rule of thumb, one could expect better solubility in polar solvents compared to non-polar ones, particularly due to its functional groups.

Interesting facts

Interesting Facts about 3-(5-nitro-2-furyl)prop-2-enoic acid

3-(5-nitro-2-furyl)prop-2-enoic acid, commonly referred to within the realm of organic chemistry, showcases an intriguing molecular structure that links ecologically significant functionalities with potential applications in various fields.

Key Characteristics

  • Origin of the Name: The name derives from its unique components. The nitro group and furan ring represent significant features that influence the compound's reactivity and properties.
  • Biological Activity: Many nitro heterocycles, including 5-nitro-2-furyl derivatives, have been researched for their potential biological activities. Some studies suggest that they exhibit antimicrobial and anticancer properties, making them of interest in drug development.
  • Industrial Use: This compound can serve as an important intermediates in the synthesis of other chemical products, showcasing its versatility for various industrial applications.

Chemical Behavior

The compound's reactivity can be attributed to its functional groups, which may participate in numerous reactions including nucleophilic attacks and *substitutions*. Such behaviors render it useful in the formation of more complex molecules.

Cultural Relevance

Interestingly, compounds with nitro substituents have often been viewed with caution due to their association with explosives; however, the context is entirely different in this case. The presence of the furan moiety adds a layer of structural diversity that enhances discussion in both academic and practical chemistry realms.

Further Research

Ongoing research into the utilities and effects of 3-(5-nitro-2-furyl)prop-2-enoic acid opens avenues for:

  • Investigating its role in organic synthesis
  • Exploring its biological mechanisms
  • Understanding environmental interactions

In summary, 3-(5-nitro-2-furyl)prop-2-enoic acid is more than just a geometric arrangement of atoms; it represents a fascinating intersection of chemistry, biology, and potential industrial applications, underscoring the importance of functional compounds in advancing scientific knowledge.

Synonyms
LWOWNIPZHGWKNR-UHFFFAOYSA-N
BCP31033
AKOS016042134
SB61591
DB-054296
5-Nitro-2-furanacrylic acid;Nitrofurylacrylamide;Trans-5-nitro-2-furanacrylic acid