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Gramine hydrochloride

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Identification
Molecular formula
C11H15ClN2
CAS number
65-40-5
IUPAC name
3-(5,5-dimethylpyrrolidin-1-ium-2-yl)-1H-indole;chloride
State
State

At room temperature, Gramine hydrochloride is generally in a solid state. It is soluble in water and may form a solution upon dissolution. It is stable under standard conditions.

Melting point (Celsius)
155.00
Melting point (Kelvin)
428.15
Boiling point (Celsius)
264.90
Boiling point (Kelvin)
538.05
General information
Molecular weight
212.26g/mol
Molar mass
232.7350g/mol
Density
1.0900g/cm3
Appearence

Gramine hydrochloride typically appears as an off-white to yellow crystalline solid. The compound may appear as fine powder or granules. Depending on storage conditions and environmental factors like humidity, the appearance might slightly change.

Comment on solubility

Solubility of 3-(5,5-dimethylpyrrolidin-1-ium-2-yl)-1H-indole;chloride

The solubility of 3-(5,5-dimethylpyrrolidin-1-ium-2-yl)-1H-indole;chloride in various solvents is a fascinating aspect to consider. Here are some key points regarding its solubility:

  • Water Solubility: This compound is expected to be soluble in water due to the presence of the quaternary ammonium group, which tends to increase hydrophilicity.
  • Organic Solvents: It may exhibit solubility in polar organic solvents like methanol and ethanol, though the exact solubility can vary based on concentration and temperature.
  • Insolubility in Non-Polar Solvents: Conversely, 3-(5,5-dimethylpyrrolidin-1-ium-2-yl)-1H-indole;chloride is likely insoluble in non-polar solvents such as hexane or benzene, owing to its ionic nature.

Understanding the solubility of this compound is crucial for various applications, especially in biological and chemical research. It is important to conduct specific experiments to determine precise solubility parameters under varying conditions.

Interesting facts

Interesting Facts about 3-(5,5-dimethylpyrrolidin-1-ium-2-yl)-1H-indole;chloride

3-(5,5-dimethylpyrrolidin-1-ium-2-yl)-1H-indole;chloride is a fascinating compound that intricately combines the features of indole and a pyrrolidine moiety. This unique structure contributes to its intriguing properties and potential applications in various fields.

1. Structural Characteristics

  • Indole Backbone: The indole moiety is known for its fundamental role in many biological systems, serving as a building block for various natural products.
  • Pyrrolidine Influence: The inclusion of a pyrrolidine ring adds stability and can influence the compound's interaction with biological targets.

2. Applications

  • Pharmaceutical Research: Compounds similar to this one have been studied for their potential in drug development, particularly in neurology and psychiatry.
  • Biological Activity: Its structural components suggest possible activities as a neurotransmitter modulator, which could lead to new therapeutic pathways.

3. Synthesis and Modification

The synthesis of such compounds often involves complex organic reactions, showcasing the creativity and skills required in modern chemistry. Fine-tuning the pyrrolidine and indole moieties through different synthetic pathways allows chemists to optimize properties and functionality.

4. Noteworthy Class of Compounds

This compound belongs to a class known as alkaloids, famous for their psychoactive properties. Alkaloids have been widely used throughout history in various cultures for their medicinal qualities.

In conclusion, 3-(5,5-dimethylpyrrolidin-1-ium-2-yl)-1H-indole;chloride exemplifies the beauty and complexity of chemical research. Understanding its properties could lead to significant advancements in science and medicine.

Synonyms
3-(5,5-Dimethyl-2-pyrrolidinyl)indole hydrochloride
19134-08-8
INDOLE, 3-(5,5-DIMETHYL-2-PYRROLIDINYL)-, HYDROCHLORIDE