3-(5,5-dimethylpyrrolidin-2-yl)-1H-indole

Identification

Molecular formula

C₁₄H₁₈N₂

CAS number

Not Available

IUPAC name

3-(5,5-dimethylpyrrolidin-2-yl)-1H-indole

State

At room temperature, 3-(5,5-dimethylpyrrolidin-2-yl)-1H-indole is commonly found as a solid due to its relatively high melting point above ambient temperature. This compound is stable under standard conditions of storage and handling.

Melting point (Celsius)

155.00

Melting point (Kelvin)

428.15

Boiling point (Celsius)

430.00

Boiling point (Kelvin)

703.15

General information

Molecular weight

230.34g/mol

Molar mass

230.3350g/mol

Density

1.1800g/cm³

Appearence

3-(5,5-dimethylpyrrolidin-2-yl)-1H-indole typically appears as a crystalline solid. The compound exhibits a color range from off-white to light yellow, dependent on its purity and environmental conditions. This substance can exhibit a polihedral crystal structure.

Comment on solubility

Solubility of 3-(5,5-dimethylpyrrolidin-2-yl)-1H-indole

The solubility of 3-(5,5-dimethylpyrrolidin-2-yl)-1H-indole can be influenced by several factors, including its molecular structure and the presence of functional groups. Generally, solubility behaviors can be summarized as follows:

Polarity: The compound contains a pyrrolidine moiety which can enhance solubility in polar solvents due to hydrogen bonding.
Solvent Interactions: It is likely to be more soluble in alcohols or dimethyl sulfoxide (DMSO) than in purely non-polar solvents, reflecting the influence of polar functional groups.
Temperature Effects: As with many organic compounds, increasing temperature usually increases solubility, although this can vary significantly based on the solvent.
Concentration: At higher concentrations, solubility can exhibit non-linear behavior due to interactions between molecules, which can affect dissolution rates.

It is important to note that experimental data is essential for accurately determining the solubility of 3-(5,5-dimethylpyrrolidin-2-yl)-1H-indole in specific solvents. Always consult empirical studies to confirm theoretical predictions, as practical conditions often reveal solubility characteristics that may not be apparent through calculation alone.

In conclusion, the solubility profile of this compound highlights the complex interplay of structure, solvent properties, and environmental conditions, making it a fascinating subject for further research.

Interesting facts

Interesting Facts About 3-(5,5-Dimethylpyrrolidin-2-yl)-1H-Indole

3-(5,5-Dimethylpyrrolidin-2-yl)-1H-indole is a fascinating compound that belongs to the class of indole derivatives, which are known for their diverse biological activities. Here are some interesting insights into this intriguing molecule:

Indole Background: Indole itself is a crucial structure in many natural products and pharmaceuticals. It acts as a building block for various compounds, including neurotransmitters, alkaloids, and even tryptophan, an essential amino acid.
Versatile Chemistry: The presence of the dimethylpyrrolidine group enhances the structural complexity and can influence the compound's reactivity. This makes it a promising candidate in medicinal chemistry and drug design.
Biological Relevance: Compounds that contain indole structures have been linked to numerous biological processes. They can exhibit activities such as anti-inflammatory, antimicrobial, and antitumor effects, making them important in pharmaceutical research.
Structural Diversity: The incorporation of the pyrrolidine ring presents a unique modification that may affect the lipophilicity and pharmacological profile of the compound, paving the way for new therapeutic agents.
Research Potential: Given its structural uniqueness, 3-(5,5-Dimethylpyrrolidin-2-yl)-1H-indole could serve as a scaffold in the development of novel drugs, potentially targeting various biochemical pathways.

As a chemist exploring the vast landscape of organic compounds, understanding the intricate relationships between structure and activity is crucial. This particular compound showcases the creativity inherent in synthetic chemistry and emphasizes the importance of structure-activity relationships in drug development.

In the words of renowned chemist Linus Pauling, “The best way to have a good idea is to have a lot of ideas.” With compounds like this, the possibilities are indeed limitless!