Methylene Blue | Solubility of Things

Identification

Molecular formula

C₁₆H₁₈N₃SCl

CAS number

61-73-4

IUPAC name

3-(5,5-dioxophenothiazin-10-yl)-N,N,2-trimethyl-propan-1-amine

State

At room temperature, methylene blue is in a solid-state, existing as a crystalline powder that is typically dark green in color. However, its aqueous solutions are vividly blue.

Melting point (Celsius)

100.00

Melting point (Kelvin)

373.00

Boiling point (Celsius)

250.00

Boiling point (Kelvin)

523.00

General information

Molecular weight

319.85g/mol

Molar mass

319.8520g/mol

Density

1.5630g/cm³

Appearence

Methylene blue is a dark green solid which, when dissolved in water, gives off a distinct deep blue color. It is typically available in the form of a crystalline powder or as crystals. This striking coloration is highly characteristic and is often used in dye applications.

Comment on solubility

Solubility of 3-(5,5-dioxophenothiazin-10-yl)-N,N,2-trimethyl-propan-1-amine

The compound 3-(5,5-dioxophenothiazin-10-yl)-N,N,2-trimethyl-propan-1-amine exhibits interesting solubility characteristics, which can be influenced by various factors. Understanding its solubility is essential in applications such as pharmaceuticals and environmental chemistry.

Here are some crucial points to note regarding its solubility:

Polar vs. Non-Polar Solvents: This compound may show varying solubility in polar and non-polar solvents. Due to the presence of amine groups, it is expected to have better solubility in polar solvents like water and ethanol compared to non-polar solvents.
Temperature Influence: As with many organic compounds, increased temperature generally enhances solubility. Higher temperatures can significantly aid in dissolving solid forms of the compound.
pH Sensitivity: The solubility can also be affected by the pH of the solution. In more acidic or basic environments, the ionization state of the amine groups can change, influencing how well the compound dissolves.
Complex Formation: This compound may form complexes with other molecules, which can further complicate its solubility profile. Such interactions can either enhance or inhibit solubility.

In summary, while the specific solubility data for 3-(5,5-dioxophenothiazin-10-yl)-N,N,2-trimethyl-propan-1-amine requires further empirical investigation, factors like solvent polarity, temperature, pH, and potential complexation role play vital roles in determining its overall solubility. Understanding these aspects is key in optimizing its usage in various applications.

Interesting facts

Interesting Facts about 3-(5,5-Dioxophenothiazin-10-yl)-N,N,2-trimethyl-propan-1-amine

This compound, known for its complex structure, is part of a class of chemicals that often have significant biological activity. Here are some intriguing insights about this compound:

Pharmacological Significance: Many compounds related to phenothiazine derivatives exhibit neuroleptic properties, which are essential for the treatment of various psychiatric disorders.
Structural Characteristics: The presence of both a thiazine and a tertiary amine in its structure contributes to its unique chemical behavior, affecting how it interacts with biological systems.
Potential Uses: Research indicates that compounds similar to this can be explored for their potential in developing new therapeutic agents, particularly in the field of antipsychotic medications.
Research Focus: Ongoing studies are investigating how the modifications in the molecular structure influence pharmacodynamics and pharmacokinetics, which can lead to better-targeted therapies.

As noted by researchers, “Understanding the intricate balance between structure and function in these compounds opens up new avenues for drug development.”

In conclusion, 3-(5,5-dioxophenothiazin-10-yl)-N,N,2-trimethyl-propan-1-amine is a prime example of how structural variation can lead to diverse biological activities, thus paving the way for innovations in medicinal chemistry.

Synonyms

Oxomemazine

3689-50-7

Dysedon

Doxergan

Imakol

Oxymemazine

Dosegran

Oxomemazina

Alimemazine S,S-dioxide

Oxomemazinum

Oplex

Exe-top

Oxomemazine [INN:DCF]

Trimeprazine 5,5-dioxide

Oxomemazinum [INN-Latin]

RP 6847

Oxomemazina [INN-Spanish]

EINECS 222-996-8

Doxergan (TN)

Oxomemazine (INN)

RP-6847

BRN 0289178

10-(3-(Dimethylamino)-2-methylpropyl)phenothiazine 5,5-dioxide

10-(3-(Dimethylamino)-2-methylpropyl)phenothiazine-5,5-dioxide

6847 R.P.

305MB38V1C

OXOMEMAZINE [MI]

OXOMEMAZINE [INN]

6487-RP

6847-RP

10H-Phenothiazine-10-propanamine, N,N,.beta.-trimethyl-, 5,5-dioxide

OXOMEMAZINE [MART.]

OXOMEMAZINE [WHO-DD]

DTXSID5023405

4-27-00-01270 (Beilstein Handbook Reference)

Dioxo-9,9-(dimethylamino-3-methyl-2-propyl)-10-phenothiazine [French]

PHENOTHIAZINE, 10-(3-(DIMETHYLAMINO)-2-METHYLPROPYL)-, 5,5-DIOXIDE

(+-)-Oxomemazine

Dioxo-9,9-(dimethylamino-3-methyl-2-propyl)-10-phenothiazine

Oxomemazinum (INN-Latin)

Oxomemazina (INN-Spanish)

OXOMEMAZINE (MART.)

Phenothiazine, 10-[3-(dimethylamino)-2-methylpropyl]-, 5,5-dioxide

10-(3-(dimethylamino)-2-methylpropyl)-10H-5lambda6-phenothiazine-5,5-dione

10-[3-(dimethylamino)-2-methylpropyl]-10H-5lambda6-phenothiazine-5,5-dione

DTXCID103405

R06AD08

10H-Phenothiazine-10-propanamine, N,N,beta-trimethyl-, 5,5-dioxide

222-996-8

10-(3-(diMethylaMino)-2-Methylpropyl)-10H-phenothiazine 5,5-dioxide

(+)-Oxomemazine

(-)-Oxomemazine

3-(5,5-dioxophenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine

Oxomemazine, (+)-

Oxomemazine, (-)-

Q824SGH3RN

(+/-)-OXOMEMAZINE

5GP9538P4S

174508-14-6

Oxomemazin

Trimeprazine Sulphone; Oxomemazine

174508-13-5

NCGC00182075-03

UNII-305MB38V1C

MFCD00868197

UNII-Q824SGH3RN

MLS006009989

SCHEMBL423634

UNII-5GP9538P4S

CHEMBL2104734

CHEBI:135408

ARD14338

Oxomemazine 1.0 mg/ml in Methanol

AKOS015962134

6487 RP

6847 RP

DB13820

NCGC00182075-02

1ST14338

AC-15943

DA-76517

MS-24971

SMR004701064

HY-136587

CS-0131898

NS00002586

D07401

F20164

SR-01000883964

Q3359071

SR-01000883964-1

10H-Phenothiazine-10-propanamine, N,N,beta-trimethyl-, 5,5-dioxide, (+)-

10H-Phenothiazine-10-propanamine, N,N,beta-trimethyl-, 5,5-dioxide, (-)-

3-(5,5-Dioxido-10H-phenothiazin-10-yl)-N,N,2-trimethyl-1-propanamine #

3-(5,5-dioxido-10H-phenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine

10H-PHENOTHIAZINE-10-PROPANAMINE, N,N,.BETA.-TRIMETHYL-, 5,5-DIOXIDE, (+)-

10H-PHENOTHIAZINE-10-PROPANAMINE, N,N,.BETA.-TRIMETHYL-, 5,5-DIOXIDE, (-)-