Desipramine | Solubility of Things

Identification

Molecular formula

C₁₈H₂₂N₂

CAS number

50-47-5

IUPAC name

3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N,2-trimethyl-propan-1-amine

State

At room temperature, desipramine is in a solid state as a crystalline powder.

Melting point (Celsius)

166.00

Melting point (Kelvin)

439.15

Boiling point (Celsius)

379.80

Boiling point (Kelvin)

652.95

General information

Molecular weight

266.39g/mol

Molar mass

266.3910g/mol

Density

1.1450g/cm³

Appearence

Desipramine typically appears as a white to off-white crystalline powder. It is usually odorless and has a bitter taste.

Comment on solubility

Solubility of 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N,2-trimethyl-propan-1-amine

The compound 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N,2-trimethyl-propan-1-amine, with the chemical formula C₁₈H₂₂N₂, displays intriguing properties with regard to its solubility profile.

General Solubility Characteristics

Understanding the solubility of this compound involves several factors:

Solvent Interaction: The solubility can significantly differ based on the solvent used; polar solvents like water may show limited solubility due to the organic nature of the compound.
Temperature Influence: The solubility might increase with higher temperatures, allowing for greater molecular interaction and dissolution.
pH Levels: Given its amine functional groups, solubility could also be affected by changes in pH, potentially enhancing solubility in acidic environments.

Miscellaneous Factors

It's also important to note that the structural complexity of the compound can influence solubility:

Hydrophobic Regions: The presence of multiple aromatic rings can impart hydrophobic characteristics, which could hinder solubility in aqueous solutions.
Functional Groups: The amine group may contribute to some degree of polar interactions, but overall solubility is likely to be low in typical solvent scenarios.
Crystallinity: The solid-state packing of the compound can lead to varied solubility rates based on its crystalline form.

In conclusion, the solubility of 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N,2-trimethyl-propan-1-amine is influenced by a complex interplay of structural and environmental factors, making its solubility an intriguing aspect for further exploration.

Interesting facts

Exploring 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N,2-trimethyl-propan-1-amine

This compound, known for its complex structure, belongs to a class of chemicals that are particularly intriguing in the realm of medicinal chemistry. Here are some captivating aspects:

Pharmaceutical Potential: Compounds like this one are often studied for their potential therapeutic uses, especially in the treatment of neurological disorders and mood-related conditions.
Chemical Complexity: The presence of the dihydrobenzo[b][1]benzazepin moiety contributes to its structural intricacies, with multiple fused rings enhancing interactions with biological targets.
Structure-Activity Relationship: Understanding how variations in its structure affect activity is key. Scientists frequently explore these relationships to develop more effective drugs.
Synthesis and Reactions: This compound can be synthesized through intricate chemical reactions, making it a worthwhile subject of study in organic synthesis courses.
Research Interest: The unique characteristics of this compound encourage continued research in various fields, including organic chemistry, pharmacology, and material science.

As one can see, the study of 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N,2-trimethyl-propan-1-amine opens doors to numerous scientific inquiries, where unraveling its properties could lead to significant advancements in medicinal therapies and a deeper understanding of chemical behaviors.

Synonyms

trimipramine

Trimeprimine

739-71-9

Surmontil

Trimeproprimine

Sapilent

beta-Methylimipramine

Trimeprimina

Trimipramina

Trimipraminum

Trimeprimina [Italian]

(+)-Trimipramine

(-)-Trimipramine

7162 RP

Trimipraminum [INN-Latin]

Trimipramina [INN-Spanish]

IL 6001

3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N,2-trimethylpropan-1-amine

FI 6120

IL-6001

RP-7162

EINECS 212-008-3

UNII-6S082C9NDT

3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N,2-trimethylpropan-1-amine

5-(3-(Dimethylamino)-2-methylpropyl)-10,11-dihydro-5H-dibenz(b,f)azepine

6S082C9NDT

CHEBI:9738

2'-Metil-3'-dimetilamino-propil-5-iminodibenzile

1-(3-Dimethylamino-2-methylpropyl)-4,5-dihydro-2,3:6,7-dibenzazepine

10,11-Dihydro-5-(3-dimethylamino-2-methylpropyl)-5H-dibenz(b,f)azepine

Surmontyl

3564-75-8

CHEMBL644

7162-RP

10,11-dihydro-N,N,beta-trimethyl-5H-dibenz[b,f]azepine-5-propanamine

BRN 1321466

QJ9MUH57H8

5-[3-(dimethylamino)-2-methylpropyl]-10,11-dihydro-5H-dibenz[b,f]azepine

5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N,N,beta-trimethyl-

5-(gamma-Dimethylamino-beta-methylpropyl)-10,11-dihydro-5H-dibenzo(b,f)azepine

5H-Dibenz(b,f)azepine, 10,11-dihydro-5-(3-(dimethylamino)-2-methylpropyl)-

3564-66-7

Trimeproprimin

DTXSID8023715

10,11 Dihydro-N,N,beta-trimethyl-5H-dibenz(b,f)azepine-5-propanamine

5-(gamma-dimethylamino-beta-methylpropyl)-10,11-dihydro-5H-dibenzo[b,f]azepine

5H-Dibenz(b,f)azepine, 5-(3-(dimethylamino)-2-methylpropyl)-10,11-dihydro-, (-)-

9K5931C1H5

Rhotrimine

5H-Dibenz(b,f)azepine, 5-(3-(dimethylamino)-2-methylpropyl)-10,11-dihydro-

5H-Dibenz[b,f]azepine-5-propanamine, 10,11-dihydro-N,N,.beta.-trimethyl-

Trimipraminum (INN-Latin)

Trimipramina (INN-Spanish)

TRIMIPRAMINE (MART.)

TRIMIPRAMINE [MART.]

5-20-08-00099 (Beilstein Handbook Reference)

Trimipramine [USAN:INN:BAN]

5H-Dibenz[b,f]azepine, 5-[3-(dimethylamino)-2-methylpropyl]-10,11-dihydro-

Trimipramine (USAN/INN)

UNII-QJ9MUH57H8

10633 RP

10645 RP

2'-Metil-3'-dimetilamino-propil-5-iminodibenzile [Italian]

5H-Dibenz[b,f]azepine-5-propanamine, 10,11-dihydro-N,N,beta-trimethyl-

UNII-9K5931C1H5

10,11-DIHYDRO-N,N,BETA-TRIMETHYL-5H-DIBENZ(B,F)AZEPINE-5-PROPANAMINE

3-(10,11-dihydro-5H-dibenzo(b,f)azepin-5-yl)-N,N,2-trimethylpropan-1-amine

5H-DIBENZ(B,F)AZEPINE-5-PROPANAMINE, 10,11-DIHYDRO-N,N,.BETA.-TRIMETHYL-

Spectrum_001422

.beta.-Methylimipramine

Prestwick0_000806

Prestwick1_000806

Prestwick2_000806

Prestwick3_000806

Spectrum2_001530

Spectrum3_001151

Spectrum4_000759

Spectrum5_001052

TRIMIPRAMINE [MI]

TRIMIPRAMINE [INN]

TRIMIPRAMINE [USAN]

5H-Dibenz(b,f)azepine, 10,11-dihydro-5-(3-(dimethylamino)-2-methylpropyl)-, (+)-

5H-Dibenz(b,f)azepine, 10,11-dihydro-5-(3-(dimethylamino)-2-methylpropyl)-, (-)-

5H-Dibenz(b,f)azepine, 5-(3-(dimethylamino)-2-methylpropyl)-10,11-dihydro-, (+)-

TRIMIPRAMINE [VANDF]

Lopac0_001156

Oprea1_375679

SCHEMBL35144

BSPBio_000671

BSPBio_002701

KBioGR_001118

KBioSS_001902

DivK1c_000093

TRIMIPRAMINE [WHO-DD]

TRIMIPRAMINE, (+)-

TRIMIPRAMINE, (-)-

SPBio_001320

SPBio_002592

BPBio1_000739

DTXCID003715

GTPL7317

HY-B1213A

KBio1_000093

KBio2_001902

KBio2_004470

KBio2_007038

KBio3_002201

N06AA06

NINDS_000093

BCP06247

Trimipramine 1.0 mg/ml in Methanol

BDBM50240410

STL483796

AKOS015962182

CCG-205230

DB00726

FI-6120

SDCCGSBI-0051123.P004

5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N,N,beta-trimethyl-, (+)-

IDI1_000093

NCGC00016013-02

NCGC00016013-03

NCGC00016013-11

NCGC00162356-01

AC-15969

RP-10663

SBI-0051123.P003

AB00053646

CS-0013853

NS00000421

D00394

AB00053646_10

AB00053646_11

EN300-24410256

L000969

Q423498

BRD-A19195498-050-05-9

BRD-A19195498-050-09-1

BRD-A19195498-050-13-3

BRD-A19195498-050-14-1

3-(10,11-Dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N,2-trimethyl-1-propanamine

3-(10,11-Dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N,2-trimethyl-1-propanamine #

3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N,2-trimethyl-propan-1-amine

5-(.gamma.-Dimethylamino-.beta.-methylpropyl)-10,11-dihydro-5H-dibenzo(b,f)azepine

5H-DIBENZ(B,F)AZEPINE, 5-(3-(DIMETHYLAMINO)-2-METHYLPROPYL)-10,11-DIHYDRO-, D-

5H-DIBENZ(B,F)AZEPINE-5-PROPANAMINE, 10,11-DIHYDRO-N,N,.BETA.-TRIMETHYL-, (+)-

5H-DIBENZ(B,F)AZEPINE-5-PROPANAMINE, 10,11-DIHYDRO-N,N,.BETA.-TRIMETHYL-, (-)-

5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N,N,beta-trimethyl-, (-)-

(3-{2-azatricyclo[9.4.0.0,3,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-yl}-2-methylpropyl)dimethylamine

(3-{2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-yl}-2-methylpropyl)dimethylamine

212-008-3

5H-Dibenz[b,f]azepine-5-propanamine, 10,11-dihydro-N,N,beta.-trimethyl-, (2Z)-2-butenedioate (1:1)

InChI=1/C20H26N2/c1-16(14-21(2)3)15-22-19-10-6-4-8-17(19)12-13-18-9-5-7-11-20(18)22/h4-11,16H,12-15H2,1-3H