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Forskolin

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Identification
Molecular formula
C22H34O7
CAS number
66575-29-9
IUPAC name
3-[6-(1,2,4a-trimethyl-5-methylene-decalin-1-yl)-1-hydroxy-4-methyl-hex-3-enyl]-2-hydroxy-2H-furan-5-one
State
State

Forskolin is a solid at room temperature and is generally available in the form of a powder for extraction or research purposes.

Melting point (Celsius)
215.00
Melting point (Kelvin)
488.00
Boiling point (Celsius)
585.30
Boiling point (Kelvin)
858.50
General information
Molecular weight
410.50g/mol
Molar mass
410.4900g/mol
Density
1.3110g/cm3
Appearence

Forskolin is typically found as a crystalline compound. It can appear in various shades of white or off-white when purified. The solid form is usually seen in laboratory settings where it is isolated for study or industrial application.

Comment on solubility

Solubility of 3-[6-(1,2,4a-trimethyl-5-methylene-decalin-1-yl)-1-hydroxy-4-methyl-hex-3-enyl]-2-hydroxy-2H-furan-5-one

The solubility of the compound C22H34O7 can be understood through various factors that influence how molecules interact with solvents. Here are some key points to consider:

  • Polarity: The presence of hydroxyl groups (–OH) in the structure suggests a degree of polarity, which typically enhances solubility in polar solvents such as water.
  • Hydrophobic Regions: The large hydrocarbon framework of this compound, particularly the decalin structure, may hinder solubility in highly polar environments, potentially leading to limited solubility in water.
  • Solvent Compatibility: The solubility in organic solvents such as ethanol, methanol, or acetone is likely to be better compared to aqueous solutions due to the overall hydrophobic characteristics combined with polar functional groups.
  • Temperature: Solubility can increase with temperature, suggesting that heating the solution could enhance the dissolution of this compound.

In conclusion, while the presence of polar functional groups in C22H34O7 indicates a potential for solubility in polar solvents, the extensive hydrophobic nature of its structure may pose challenges. Therefore, it is important to evaluate both the nature of the solvent and the temperature conditions to achieve optimal solubility.

Interesting facts

Interesting Facts about 3-[6-(1,2,4a-trimethyl-5-methylene-decalin-1-yl)-1-hydroxy-4-methyl-hex-3-enyl]-2-hydroxy-2H-furan-5-one

This complex compound presents a fascinating structure that blends both natural and synthetic elements, making it a unique subject of study in the realm of organic chemistry. Given its intricate design, let’s dive into some captivating aspects:

  • Unique Structural Features: The presence of a furan ring and a decalin system is noteworthy. This combination enhances the compound's potential reactivity and opens pathways for derivative synthesis.
  • Biological Significance: Compounds of this nature often exhibit biological activity. Their modified structures may be explored for pharmacological properties, including anti-inflammatory or anti-tumor effects.
  • Application in Flavor Chemistry: The structure suggests applications in the field of flavor and fragrance. Compounds containing similar furan moieties are commonly used in the food industry for their desirable aroma.
  • Natural Sources: Its nature suggests a potential occurrence in certain plant species, hinting at a possible role in ecological interactions—especially in pollination processes or in plant defense mechanisms.

As you study this compound, consider the diversity it represents in the chemistry landscape. The synthesis and modification of such structures not only enhance our understanding of organic compounds but also contribute to the development of novel substances with impactful uses in various industries.

In the words of renowned chemist Linus Pauling, "The best way to have a good idea is to have lots of ideas." This compound's complexity indeed offers many avenues for exploration and innovation!