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Ambenonium iodide

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Identification
Molecular formula
C20H38N4O2I2
CAS number
3485-14-1
IUPAC name
3-[6-[3-[diethyl(methyl)ammonio]propoxy]pyridazin-3-yl]oxypropyl-diethyl-methyl-ammonium;diiodide
State
State

At room temperature, ambenonium iodide is typically in a solid state. It is often provided in the form of a powder that is used for pharmaceutical applications.

Melting point (Celsius)
220.00
Melting point (Kelvin)
493.15
Boiling point (Celsius)
381.04
Boiling point (Kelvin)
654.19
General information
Molecular weight
618.33g/mol
Molar mass
618.3290g/mol
Density
2.0400g/cm3
Appearence

Ambenonium iodide appears as a white to off-white crystalline powder. It is stable under normal temperatures and pressures and is known for its hygroscopic properties, meaning it can absorb moisture from the environment.

Comment on solubility

Solubility of 3-[6-[3-[diethyl(methyl)ammonio]propoxy]pyridazin-3-yl]oxypropyl-diethyl-methyl-ammonium;diiodide

The solubility of the compound 3-[6-[3-[diethyl(methyl)ammonio]propoxy]pyridazin-3-yl]oxypropyl-diethyl-methyl-ammonium; diiodide can be intriguingly assessed based on its chemical structure and functional groups. Generally, the presence of multiple ammonium groups suggests that the compound may exhibit certain solubility characteristics, particularly in polar solvents such as water. Here are some key points to consider:

  • Polarity: The presence of ionic diiodide ions could enhance its solubility in water and other polar solvents.
  • Hydrogen Bonding: The functional groups may engage in hydrogen bonding, potentially increasing interaction with solvents.
  • Solvent Choice: Non-polar solvents would likely yield poor solubility due to the compound's ionic character.
  • Temperature Effects: Solubility may increase with temperature, which is a common characteristic for many ionic compounds.

As with many quaternary ammonium salts, the solubility behavior can vary significantly depending on the solvent used, and empirical testing is often necessary to determine precise solubility levels. In summary, while predictions about solubility can be made based on theoretical considerations, practical solubility measurements offer the most reliable insights.

Interesting facts

Interesting Facts about 3-[6-[3-[diethyl(methyl)ammonio]propoxy]pyridazin-3-yl]oxypropyl-diethyl-methyl-ammonium;diiodide

This compound, with a complex structure, falls within the category of quaternary ammonium salts, which are recognized for their unique properties and a variety of applications in chemistry and industry. Here are some noteworthy points about this intriguing compound:

  • Quaternary Ammonium Features: The presence of diethyl(methyl)ammonio groups in this compound contributes to its quaternary nature, making it highly cationic. This cationic character is significant in its interaction with biological membranes, enhancing its penetration abilities.
  • Biological Applications: Compounds like this are often investigated for their potential role as antimicrobial agents. Their ability to disrupt microbial cell membranes is a focus of ongoing research, particularly in the medical and agricultural sectors.
  • Structural Complexity: The multi-functionalized structure, which includes a pyridazin moiety, offers diverse possibilities for modifications that can lead to new derivatives, each with distinct activities. Such adaptations can potentially alter solubility, stability, and biological efficacy.
  • Role in Drug Development: This compound could serve as a lead scaffold for drug design, particularly in developing therapies that target ion channels or neurotransmitter systems due to its ammonium-functionalized nature.

As we continue to explore the capabilities of such compounds, the implications in various fields, including medicinal chemistry, materials science, and nanotechnology are vast. Research into their interactions with biological systems may unlock new pathways for therapeutics and diagnostic tools.

In summary, the compound 3-[6-[3-[diethyl(methyl)ammonio]propoxy]pyridazin-3-yl]oxypropyl-diethyl-methyl-ammonium;diiodide stands out not only for its chemical complexity but also for its potential applications, highlighting the endless possibilities in chemical research.

Synonyms
WIN 4981
3572-35-8
3,6-Bis(3-diethylaminopropoxy)pyridazine bis-methiodide
AMMONIUM, (3,6-PYRIDAZINEDIYLBIS(OXYTRIMETHYLENE))BIS(DIETHYLMETHYL-, DIIODIDE
(3,6-Pyridazinediylbis(oxytrimethylene))bis(diethylmethylammonium iodide)
1-Propanaminium, 3,3'-(3,6-pyridazinediylbis(oxy))bis(N,N-diethyl-N-methyl-, diiodide
1-Propanaminium, 3,3'-(3,6-pyridazinediylbis(oxy))bis(N,N-diethyl-N-methyl-, diiodide (9CI)
DTXSID80957129
3,3'-[Pyridazine-3,6-diylbis(oxy)]bis(N,N-diethyl-N-methylpropan-1-aminium) diiodide