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Forskolin

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Identification
Molecular formula
C22H34O7
CAS number
66575-29-9
IUPAC name
[3-(6-acetoxy-1,5,9-trimethyl-deca-2,4,8-trienylidene)-6-(hydroxymethyl)-3a,6,9a-trimethyl-2-oxo-1,4,5,5a,7,8,9,9b-octahydrocyclopenta[a]naphthalen-7-yl] acetate
State
State

At room temperature, forskolin is typically solid.

Melting point (Celsius)
233.00
Melting point (Kelvin)
506.15
Boiling point (Celsius)
240.00
Boiling point (Kelvin)
513.15
General information
Molecular weight
410.50g/mol
Molar mass
410.4970g/mol
Density
0.8602g/cm3
Appearence

Forskolin appears as an off-white crystalline powder. It is commonly derived from the roots of the plant Plectranthus barbatus (Coleus forskohlii).

Comment on solubility

Solubility of 3-(6-acetoxy-1,5,9-trimethyl-deca-2,4,8-trienylidene)-6-(hydroxymethyl)-3a,6,9a-trimethyl-2-oxo-1,4,5,5a,7,8,9,9b-octahydrocyclopenta[a]naphthalen-7-yl acetate (C22H34O7)

The solubility of complex organic compounds such as C22H34O7 can be influenced by several factors, including their molecular structure, functional groups, and the presence of polar or non-polar regions. In the case of this compound:

  • Polarity: The presence of hydroxymethyl and acetate groups suggests that this compound may engage in hydrogen bonding, which can enhance its solubility in polar solvents like water.
  • Non-polar Character: Meanwhile, the extensive hydrocarbon framework can impart hydrophobic characteristics, limiting solubility in highly polar environments.
  • Solvent Specificity: Likely to show better solubility in organic solvents such as ethanol and dichloromethane, which can accommodate both its polar and non-polar features.
  • Temperature Influence: As with many organic compounds, increased temperature may improve solubility by providing more energy to overcome intermolecular forces.

In conclusion, the solubility of this compound is likely to be moderate, depending significantly on the solvent used and environmental conditions. A careful evaluation of solvent interactions is recommended to predict solubility behavior effectively.

Interesting facts

Exploring the Intricacies of 3-(6-acetoxy-1,5,9-trimethyl-deca-2,4,8-trienylidene)-6-(hydroxymethyl)-3a,6,9a-trimethyl-2-oxo-1,4,5,5a,7,8,9,9b-octahydrocyclopenta[a]naphthalen-7-yl Acetate

This fascinating compound presents a rich tapestry of structural complexity and potential applications, making it an intriguing subject of study in the field of organic chemistry.

Key Features

  • Structural Complexity: The compound features a unique bicyclic system that integrates both naphthalene and cyclopentane structures, highlighting the diverse structural possibilities within organic molecules.
  • Functional Groups: The presence of multiple functional groups, including acetoxy, hydroxymethyl, and keto groups, suggests the potential for diverse chemical reactivity and interactions.
  • Therapeutic Potential: Given its complex structure, there may be implications for biological activity, warranting investigations into its medicinal properties or suitability as a pharmaceutical ingredient.

Interesting Insights

This compound invites chemists to consider its synthetic routes, potentially leading to novel derivations with varied functionalities. The trienylidene moiety raises questions about its stability and reactivity, providing ripe opportunities for further research.

As one delves deeper into its molecular architecture, it's essential to consider:

  • Isomeric forms – due to the number of functional groups, isomerism could greatly influence the compound's properties.
  • Reactivity studies – exploring how this compound interacts with other chemical species could unveil new pathways for synthesis or applications.

In the words of renowned chemist Robert H. Grubbs, “Chemistry is the science of transformation,” and this compound embodies that transformation with its multifaceted nature, reminding us of the endless possibilities that lie within the molecular world.

In conclusion, this compound serves as a prime example of how intricate molecular designs can lead to innovative discoveries in the realm of chemistry, making it a worthwhile topic for further research and exploration.