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Iodixanol

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Identification
Molecular formula
C35H44I6N6O15
CAS number
92339-11-2
IUPAC name
3-[[7-[3-carboxy-2,4,6-triiodo-5-[(propanoylamino)methyl]anilino]-7-oxo-heptanoyl]amino]-2,4,6-triiodo-5-[(propanoylamino)methyl]benzoic acid
State
State

At room temperature, Iodixanol is typically in the form of a solid. However, for medical applications, it is often used in a solution form. The solution is typically clear and colorless.

Melting point (Celsius)
165.00
Melting point (Kelvin)
438.15
Boiling point (Celsius)
380.00
Boiling point (Kelvin)
653.15
General information
Molecular weight
1550.20g/mol
Molar mass
1 550.2040g/mol
Density
2.0180g/cm3
Appearence

Iodixanol appears as a white to off-white crystalline powder. It is typically supplied as a sterile, aqueous solution for injection. The solution is clear and colorless to pale yellow, depending on concentration and conditions of storage.

Comment on solubility

Solubility Characteristics

The compound 3-[[7-[3-carboxy-2,4,6-triiodo-5-[(propanoylamino)methyl]anilino]-7-oxo-heptanoyl]amino]-2,4,6-triiodo-5-[(propanoylamino)methyl]benzoic acid exhibits unique solubility properties owing to its complex molecular structure. Understanding its solubility is essential for various applications, especially in pharmaceutical formulations.

Factors Influencing Solubility

Several factors contribute to the solubility of this compound:

  • Polarity: The presence of carboxylic acid groups (-COOH) enhances water solubility due to their ability to form hydrogen bonds.
  • Iodine Atoms: The triiodo groups may create steric hindrance, potentially affecting solubility in nonpolar solvents.
  • Amino Groups: The propanoylamino functionalities introduce additional polar characteristics, which can promote solubility in polar solvents.

Predicted Solubility Behavior

Based on the structural features, it is expected that:

  • The compound will exhibit solubility in polar solvents such as water or dimethyl sulfoxide (DMSO).
  • It may have limited solubility in nonpolar solvents, owing to the large and polar functional groups.
  • The solubility could be enhanced by changes in pH, especially due to the acidic groups present.

In summary, while the precise solubility specifics depend on factors such as solvent type and environmental conditions, the presence of polar groups suggests that this compound will more readily dissolve in polar environments.

Interesting facts

Discovering the Complexity of 3-[[7-[3-Carboxy-2,4,6-triiodo-5-[(propanoylamino)methyl]anilino]-7-oxo-heptanoyl]amino]-2,4,6-triiodo-5-[(propanoylamino)methyl]benzoic acid

This compound is a fascinating example of the intricate designs chemists can create. Not only does it contain multiple functional groups, but it also showcases the significant utility of iodine in organic chemistry. Here are some intriguing insights:

  • Multifunctionality: The presence of both carboxylic acid and amide groups allows this molecule to participate in various chemical reactions, making it a candidate for applications in pharmaceuticals and biotechnology.
  • Iodine’s Role: The tri-iodinated structure enhances the compound's ability to interact with biological systems, especially in imaging techniques such as X-ray or gamma-ray imaging, making it potentially useful in medical diagnostics.
  • Structural Complexity: The multiple aromatic rings offer unique electronic properties, which can lead to interesting photophysical characteristics. Such complexity is a testament to the elegance of chemical synthesis.
  • Targeted Drug Delivery: The incorporation of a propanoylamino group suggests potential for biomolecular targeting, which is essential in the development of more effective drug delivery systems.

As one exploration leads to another, the research into this compound could uncover even more potential applications and insights into its behavior, especially in biochemical environments. This will likely stimulate further investigations into its efficacy and mechanisms of action.

In the words of renowned chemist Linus Pauling: "The best way to have a good idea is to have lots of ideas." The exploration of compounds like this one showcases the limitless potential of chemical research and innovation.

Synonyms
BRN 2800721
BENZOIC ACID, 3,3'-(PIMELOYLDIIMINO)BIS(5-(PROPIONAMIDOMETHYL)-2,4,6-TRIIODO-
25901-45-5
DTXSID10180564
3,3'-(Pimeloyldiimino)bis(5-(propionamidomethyl)-2,4,6-triiodobenzoic acid)
RefChem:326959
DTXCID50103055