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Trospium Chloride

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Identification
Molecular formula
C25H30ClN2O3
CAS number
10405-02-4
IUPAC name
3-(7-chloro-5-oxo-benzo[b][1,8]naphthyridin-10-yl)propyl-dimethyl-ammonium;chloride
State
State
Trospium Chloride is a solid at room temperature. It is commonly found in a powder form, suitable for drug formulation.
Melting point (Celsius)
240.00
Melting point (Kelvin)
513.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
427.98g/mol
Molar mass
427.3390g/mol
Density
1.4780g/cm3
Appearence

Trospium Chloride appears as a white crystalline powder. It is typically supplied in a solid form and is utilized in clinical settings for its pharmacological properties.

Comment on solubility

Solubility of 3-(7-chloro-5-oxo-benzo[b][1,8]naphthyridin-10-yl)propyl-dimethyl-ammonium;chloride

The solubility of the compound 3-(7-chloro-5-oxo-benzo[b][1,8]naphthyridin-10-yl)propyl-dimethyl-ammonium;chloride can be influenced by several factors due to its complex nature. Here are some key points to consider:

  • Polarity: The presence of the quaternary ammonium structure may increase its polarity, affecting solubility in polar solvents like water.
  • Chloride Ion: The chloride ion (Cl-) can enhance the solubility of the overall compound in aqueous solutions.
  • Hydrophobic Interactions: The naphthyridinyl moiety can lead to reduced solubility in nonpolar solvents owing to hydrophobic interactions.
  • Temperature Effects: Solubility may also vary with temperature, typically increasing in hotter conditions for ionic compounds.

In general, quaternary ammonium salts tend to be soluble in polar solvents and slightly soluble in organic solvents. As noted, “overall solubility is a function of both the ionic nature and hydrophobic characteristics of the compound.” Therefore, further investigations are needed to establish precise solubility data for this specific compound in various solvents.

Interesting facts

Interesting Facts about 3-(7-Chloro-5-oxo-benzo[b][1,8]naphthyridin-10-yl)propyl-dimethyl-ammonium;chloride

This compound, often referred to in scientific literature by its systematic name, is an intriguing member of the class of compounds known as quaternary ammonium salts. Here are some notable points to consider:

  • Biological Activity: Research has indicated that compounds like this one may exhibit biological activities such as antimicrobial and antifungal properties, making them of interest in pharmaceutical applications.
  • Chemical Structure: The compound features a unique benzo[b][1,8]naphthyridine structure, which is known for its potential efficacy in binding to various biomolecules, offering possibilities for targeted drug design.
  • Mechanism of Action: As a quaternary ammonium compound, its mechanism of action typically involves disrupting cellular membranes, which can lead to cell death in pathogens.
  • Substituents: The presence of chlorine and other functional groups in its structure can greatly influence its reactivity and biological interactions, emphasizing the significance of structure-activity relationships in medicinal chemistry.
  • Future Research: As drug resistance becomes a growing concern in medicine, compounds like this are increasingly important in the search for new therapeutic agents that can combat resistant strains of bacteria and fungi.

This compound serves as a reminder of how complex chemical structures can lead to valuable biological outcomes, thus highlighting the importance of chemical innovation in the fight against disease.

Synonyms
DTXSID80951541
7-Chloro-10-(3-(dimethylamino)propyl)benzo(b)(1,8)naphthyridin-5(10H)-one--hydrogen chloride (1/1)
RefChem:1074378
DTXCID001379658
IFC-45
C 45 (pharmaceutical)
28907-45-1
IPF C-45
C 45
Benzo(b)(1,8)naphthyridin-5(10H)-one, 7-chloro-10-(3-(dimethylamino)propyl)-, monohydrochloride
7-Chloro-10-(3-dimethylaminopropyl)-benzo-(b)(1,8)-5(10H)-naphthayridone hydrochloride
Chlorowodorku 10-gamma-dwumetyloaminopropylo-7-chlorobenzo(b)-(1,8)-naftyrydonu-5 [Polish]
Chlorowodorku 10-gamma-dwumetyloaminopropylo-7-chlorobenzo(b)-(1,8)-naftyrydonu-5