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Iodixanol

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Identification
Molecular formula
C35H44I6N6O15
CAS number
92339-11-2
IUPAC name
3-[[8-[3-carboxy-2,4,6-triiodo-5-[(2-oxopyrrolidin-1-yl)methyl]anilino]-8-oxo-octanoyl]amino]-2,4,6-triiodo-5-[(2-oxopyrrolidin-1-yl)methyl]benzoic acid
State
State

At room temperature, Iodixanol is typically found in a liquid state, especially when formulated for its use in medical imaging as a contrast agent.

Melting point (Celsius)
150.00
Melting point (Kelvin)
423.15
Boiling point (Celsius)
500.00
Boiling point (Kelvin)
773.15
General information
Molecular weight
1550.24g/mol
Molar mass
1 550.2400g/mol
Density
2.0150g/cm3
Appearence

Iodixanol appears as a white to off-white powder when in solid form. However, it is commonly supplied and used as a colorless solution due to its application as a contrast agent.

Comment on solubility

Solubility of 3-[[8-[3-carboxy-2,4,6-triiodo-5-[(2-oxopyrrolidin-1-yl)methyl]anilino]-8-oxo-octanoyl]amino]-2,4,6-triiodo-5-[(2-oxopyrrolidin-1-yl)methyl]benzoic acid

The solubility of the compound 3-[[8-[3-carboxy-2,4,6-triiodo-5-[(2-oxopyrrolidin-1-yl)methyl]anilino]-8-oxo-octanoyl]amino]-2,4,6-triiodo-5-[(2-oxopyrrolidin-1-yl)methyl]benzoic acid is influenced by its complex structure, which includes multiple functional groups and iodine substitutions. In general, the solubility characteristics can be summarized as follows:

  • Solvent Compatibility: This compound may exhibit variable solubility in polar solvents such as water due to the presence of carboxylic acid groups, while its hydrophobic segments may hinder complete solubility.
  • Effect of Temperature: An increase in temperature can improve solubility depending on the solvent used, as is typical for many organic compounds.
  • Influence of pH: The solubility in aqueous solutions may significantly depend on the pH, where lower pH can facilitate protonation of the carboxyl group, potentially enhancing solubility.

It is crucial to conduct solubility tests in various solvents to determine the most suitable medium for this compound. As stated, "the solubility of a compound is a key factor in its reactivity and application." Thus, understanding its behavior in different conditions is essential for practical use and further research.

In summary, while the intricate structure of this compound poses challenges for solubility, evaluating it across diverse solvents and conditions will yield valuable insights into its properties and potential applications.

Interesting facts

Interesting Facts about the Compound 3-[[8-[3-Carboxy-2,4,6-triiodo-5-[(2-oxopyrrolidin-1-yl)methyl]anilino]-8-oxo-octanoyl]amino]-2,4,6-triiodo-5-[(2-oxopyrrolidin-1-yl)methyl]benzoic Acid

This compound is a fascinating example of modern medicinal chemistry, showcasing several striking features:

  • Complex Structural Composition: The compound contains multiple functional groups, including carboxylic acids and amides. This intricate design may enhance the compound's binding affinity to biological targets.
  • Multiple Iodine Atoms: The presence of three iodine atoms introduces unique properties such as increased molecular radioactivity, which may be beneficial in diagnostic imaging.
  • Biological Activity: The incorporation of 2-oxopyrrolidin-1-yl moieties suggests potential interactions with enzymes or receptors, opening avenues for therapeutic applications.
  • Octanoyl Chain Influence: The length of the octanoyl chain may aid in enhancing lipophilicity and cellular permeability, making it a promising candidate for drug development.

As a scientist or student in chemistry, it is crucial to explore how the structural elements of this compound contribute to its potential functionalities. A thorough understanding of its mechanistic pathways could lead to advancements in targeted therapies, particularly in oncology or infectious diseases.

Moreover, the compound's complexity exemplifies the challenges and rewards in the field of synthetic organic chemistry, where making sophisticated structures can lead to groundbreaking discoveries. The ongoing research into compounds like this one highlights the dynamic nature of drug design and development in tackling some of the most pressing health concerns today.

Synonyms
Benzoic acid, 3,3'-(suberoyldiimino)bis(5-((2-oxo-1-pyrrolidinyl)methyl)-2,4,6-triiodo-
26090-49-3
BRN 1523584
3,3'-(Suberoyldiimino)bis(5-((2-oxo-1-pyrrolidinyl)methyl)-2,4,6-triiodobenzoic acid)
DTXSID10180721