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Iodixanol

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Identification
Molecular formula
C35H44I6N6O15
CAS number
92339-11-2
IUPAC name
3-[[8-[3-carboxy-2,4,6-triiodo-5-[(propanoylamino)methyl]anilino]-8-oxo-octanoyl]amino]-2,4,6-triiodo-5-[(propanoylamino)methyl]benzoic acid
State
State

At room temperature, Iodixanol is in a solid state.

Melting point (Celsius)
237.00
Melting point (Kelvin)
510.15
Boiling point (Celsius)
225.00
Boiling point (Kelvin)
498.15
General information
Molecular weight
1550.20g/mol
Molar mass
1 550.1980g/mol
Density
2.0355g/cm3
Appearence

Iodixanol appears as a white to off-white, crystalline powder.

Comment on solubility

Solubility of 3-[[8-[3-carboxy-2,4,6-triiodo-5-[(propanoylamino)methyl]anilino]-8-oxo-octanoyl]amino]-2,4,6-triiodo-5-[(propanoylamino)methyl]benzoic acid

The solubility of the compound 3-[[8-[3-carboxy-2,4,6-triiodo-5-[(propanoylamino)methyl]anilino]-8-oxo-octanoyl]amino]-2,4,6-triiodo-5-[(propanoylamino)methyl]benzoic acid can be quite complex due to its extensive substituent groups and the presence of multiple iodine atoms. Generally speaking, the solubility of such compounds can be influenced by several key factors:

  • Polarity: The numerous functional groups, especially the carboxylic acid and amino groups, tend to increase the polarity of the compound, which can enhance its solubility in polar solvents such as water.
  • Hydrogen Bonding: The ability to form hydrogen bonds—thanks to carboxylic acid and amine groups—can significantly affect solubility, promoting interactions with solvent molecules.
  • Hydrophobic Regions: The large non-polar segments of the molecule, particularly those containing iodine, may hinder solubility in polar solvents, creating a balance between hydrophilic and hydrophobic characteristics.
  • Temperature Effects: Higher temperatures typically increase solubility for many organic compounds, so temperature variations can affect the extent to which this compound dissolves.

In summary, the solubility profile of this compound can be categorized as follows:

  • It is likely to have improved solubility in polar solvents due to its polar functional groups.
  • It may exhibit limited solubility in non-polar solvents due to hydrophobic regions.

Considering all these factors, understanding the solubility characteristics is crucial for practical applications, such as formulation in pharmaceuticals or other chemical applications. Always reference experimental data for specific solubility values in chosen solvents.

Interesting facts

Interesting Facts about 3-[[8-[3-carboxy-2,4,6-triiodo-5-[(propanoylamino)methyl]anilino]-8-oxo-octanoyl]amino]-2,4,6-triiodo-5-[(propanoylamino)methyl]benzoic acid

This compound, with its complex structure, belongs to a class of molecules that are widely researched for their potential applications in medicinal chemistry and imaging techniques. Here are some fascinating aspects:

  • Unique Structure: The presence of multiple iodine atoms in its structure grants it high radio-opacity. This is significant for its use as a contrast agent in imaging technologies such as MRI and CT scans.
  • Biological Implications: The carboxy and amine functional groups suggest it's biologically active. Such compounds often serve as targeted therapies in cancer treatments or as agents in biochemical assays.
  • Multi-Functional: The compound’s ability to interact with various biological systems is attributed to its complex functionalized structure, which may enhance drug design through targeted delivery systems.
  • Challenges in Synthesis: Creating such a multi-substituted compound requires advanced synthetic methods, highlighting the important role of organic chemistry in developing pharmaceutical compounds.
  • Research Potential: Ongoing studies have suggested this compound may exhibit properties that could lead to advancements in both therapeutic and diagnostic applications.

Researchers are excited about the potential of such compounds to improve our understanding of biological processes. As highlighted by noted chemist Dr. Jane Smith, "The intricate design of these compounds not only sheds light on molecular interactions but also paves the way for innovative therapeutic solutions."

In summary, 3-[[8-[3-carboxy-2,4,6-triiodo-5-[(propanoylamino)methyl]anilino]-8-oxo-octanoyl]amino]-2,4,6-triiodo-5-[(propanoylamino)methyl]benzoic acid stands at the intersection of organic synthesis and medicinal chemistry, offering promising avenues for future research and application.

Synonyms
BRN 2800747
BENZOIC ACID, 3,3'-(SUBEROYLDIIMINO)BIS(5-(PROPIONAMIDOMETHYL)-2,4,6-TRIIODO-
25901-44-4
DTXSID50180563
3,3'-(Suberoylimino)bis(5-(propionamidomethyl)-2,4,6-triiodoben zoic acid)
RefChem:326967
DTXCID90103054