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Cordycepin 3',5'-diphosphate

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Identification
Molecular formula
C18H24N5O14P2
CAS number
1006-67-5
IUPAC name
[3-acetamido-2-[[[5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-5-hydroxy-6-(hydroxymethyl)tetrahydropyran-4-yl] 3-hydroxytetradecanoate
State
State

This compound is typically solid at room temperature. Under standard laboratory conditions, it remains stable and unaffected by minor variations in room temperature.

Melting point (Celsius)
110.50
Melting point (Kelvin)
383.65
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
609.48g/mol
Molar mass
609.4760g/mol
Density
1.5258g/cm3
Appearence

Cordycepin 3',5'-diphosphate appears as a white to off-white solid powder. Its texture can vary from fine to slightly granular, depending on the degree of crystallization and preparation method. It has a crystalline structure typical of nucleotide analogs.

Comment on solubility

Solubility of 3-acetamido-2-[[[5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-5-hydroxy-6-(hydroxymethyl)tetrahydropyran-4-yl] 3-hydroxytetradecanoate (C18H24N5O14P2)

The solubility of this complex compound is influenced by its unique structural features. Here are some key points to consider:

  • Hydrophilic Groups: The presence of multiple hydroxyl (-OH) and phosphate (-PO4) groups enhances solubility in polar solvents, such as water.
  • Hydrophobic Elements: The hydrocarbon chain from the 3-hydroxytetradecanoate moiety may create challenges for solubility in aqueous environments, suggesting variable behavior depending on concentration and conditions.
  • Stability Factor: Structural stability can impact solubility; if the compound remains intact in solution, it may exhibit different solubility characteristics over time.
  • pH Dependency: Solubility may also vary with pH levels, suggesting that more acidic or basic conditions could significantly alter its dissolution properties.

In conclusion, while the compound may show appreciable solubility in polar solvents, the balance between hydrophilic and hydrophobic regions plays a critical role in determining its overall solubility profile. Understanding these interactions is essential for applications in pharmaceutical formulations and biochemical studies.

Interesting facts

Interesting Facts about 3-Acetamido-2-[[[5-(2,4-Dioxopyrimidin-1-yl)-3,4-Dihydroxy-Tetrahydrofuran-2-yl]Methoxy-Hydroxy-Phosphoryl]Oxy-Hydroxy-Phosphoryl]Oxy-5-Hydroxy-6-(Hydroxymethyl)Tetrahydropyran-4-yl] 3-Hydroxytetradecanoate

This complex compound, recognized for its multifaceted structure, highlights the beauty of organic synthesis and the intricate designs of molecular chemistry. Here are some fascinating insights:

  • Structural Complexity: The compound incorporates multiple functional groups, including acetamido, hydroxyl, and phosphoryl moieties, making it a prime example of how diverse chemical functionalities can coexist within a single molecular framework.
  • Biological Relevance: Compounds similar to this one, particularly those that feature pyrimidine derivatives, are often explored for their potential as pharmaceuticals. The presence of tetrahydrofuran and hydroxy functionalities suggests significant biological activity, possibly influencing enzyme interactions or cellular pathways.
  • Phosphorylation Importance: The phosphoryl groups within the structure emphasize the significance of phosphate esters in biochemistry. Phosphorylation is a critical cellular process, affecting everything from energy transfer to signal transduction.
  • Applications in Biotechnology: The molecular architecture of this compound may find applications in drug design and molecular biology, especially in the realm of nucleic acid interactions and delivery systems, where targeted action is essential.
  • Synthetic Challenges: Creating a compound of this complexity poses significant challenges in terms of synthesis, purification, and characterization, representing a rich area of research for organic chemists.

As such, this molecule not only exemplifies the intricate tapestry of life driven by chemistry but also invites ongoing research and exploration in both synthetic and medicinal chemistry. The synthesis of such compounds can lead to innovations that radically change therapeutic approaches and our understanding of biochemical processes.