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Iopamidol

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Identification
Molecular formula
C17H22I3N3O8
CAS number
60166-93-0
IUPAC name
3-acetamido-2,4,6-triiodo-5-(propanoylamino)benzoic acid
State
State

At room temperature, Iopamidol appears as a solid substance. It is typically stored away from moisture to preserve its quality as an imaging agent.

Melting point (Celsius)
188.00
Melting point (Kelvin)
461.15
Boiling point (Celsius)
330.00
Boiling point (Kelvin)
603.15
General information
Molecular weight
791.12g/mol
Molar mass
791.1230g/mol
Density
2.1869g/cm3
Appearence

Iopamidol is typically a white to off-white crystalline powder. It is odorless and has a slightly bitter taste. It is used as a contrast agent in medical imaging due to its unique iodine composition which lends opacity to X-rays.

Comment on solubility

Solubility of 3-acetamido-2,4,6-triiodo-5-(propanoylamino)benzoic acid

The solubility of 3-acetamido-2,4,6-triiodo-5-(propanoylamino)benzoic acid can be considered in terms of its structural components and functional groups. Understanding its solubility is essential for applications in pharmaceutical and biochemical contexts.

Factors Influencing Solubility:

  • Polarity: The presence of multiple iodine atoms introduces significant polarity, which can enhance solubility in polar solvents.
  • Amino Groups: The propanoylamino and acetamido groups can form hydrogen bonds, favoring solubility in water.
  • Carboxylic Acid Group: The benzoic acid component often contributes to enhanced solubility in aqueous environments, especially when deprotonated at higher pH levels.

In summary, 3-acetamido-2,4,6-triiodo-5-(propanoylamino)benzoic acid exhibits a unique solubility profile predominantly influenced by:

  1. Hydrogen bonding capacity due to amino and carboxylic functional groups.
  2. Polarity brought about by the presence of iodine substituents.
  3. Potential ionization at different pH levels, leading to increased solubility depending on the environmental conditions.

Thus, while detailed studies would be required for precise values, it can be anticipated that this compound will demonstrate a favorable solubility in polar solvents.

Interesting facts

Interesting Facts about 3-Acetamido-2,4,6-triiodo-5-(propanoylamino)benzoic Acid

3-Acetamido-2,4,6-triiodo-5-(propanoylamino)benzoic acid, a compound that showcases the intriguing intersection of organic chemistry and medicinal applications, has a variety of interesting attributes:

  • Numerous Applications: This compound, due to its structure, has potential uses in the field of pharmaceuticals and agrochemicals. Its complex molecular design allows it to interact with biological systems effectively.
  • Structural Diversity: The presence of multiple iodines in its structure makes this compound particularly fascinating for studies concerning radioiodine therapy, which is a treatment strategy predominantly used for thyroid diseases.
  • Biological Significance: Compounds like this one often exhibit interactions with biological receptors or enzymes, potentially leading to novel therapeutic agents or research tools for scientists.
  • Research Interest: The compound’s unique characteristics have drawn interest for its synthesis and study in the laboratory, making it a great candidate for exploration in organic chemistry courses.

“The beauty of compounds lies in their ability to impact science and medicine in multifaceted ways.”

This particular compound exemplifies how complex molecular architectures can be synthesized and analyzed, leading to broader applications and deeper insights in both chemistry and biological sciences.

Synonyms
BENZOIC ACID, 3-ACETAMIDO-5-PROPIONAMIDO-2,4,6-TRIIODO-
19719-02-9
BRN 3006731
3-Acetamido-5-propionamido-2,4,6-triiodobenzoic acid
SCHEMBL8494612
DTXSID60173385