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Roxarsone; Picolinate

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Identification
Molecular formula
C8H8AsNO4; C8H11NO2
CAS number
121-19-7; 114-19-8
IUPAC name
(3-acetamido-4-hydroxy-phenyl)arsonic acid;methyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate
State
State
Roxarsone: Solid. Typically, this compound exists as a crystalline solid under standard conditions of temperature and pressure.
Picolinate: Depending on the specific ester derivative, it can exist either as a liquid or solid and may have a characteristic odor.
Melting point (Celsius)
212.00
Melting point (Kelvin)
485.00
Boiling point (Celsius)
580.00
Boiling point (Kelvin)
853.00
General information
Molecular weight
263.07g/mol
Molar mass
263.0720g/mol
Density
1.7840g/cm3
Appearence

Roxarsone: Roxarsone typically appears as a white to light tan crystalline powder.

Picolinate: Picoline derivatives often appear as colorless to pale yellow liquids or solids, depending on the specific compound and conditions.

Comment on solubility

Solubility of (3-acetamido-4-hydroxy-phenyl)arsonic acid

(3-acetamido-4-hydroxy-phenyl)arsonic acid is a unique arsonic acid derivative. The presence of both acetamido and hydroxy groups contributes to its solubility characteristics. This compound tends to exhibit moderate solubility in polar solvents such as:

  • Water
  • Methanol
  • Ethanol

However, its solubility may be reduced in non-polar solvents. As a general note, the *hydrophilic* (water-attracting) functional groups enhance solubility in aqueous solutions, while the arsonic acid core could affect its interaction with different solvents.

Solubility of methyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate

Methyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate presents interesting solubility behavior primarily due to its heterocyclic structure. Compounds of this nature are often:

  • **Soluble** in polar organic solvents
  • *Slightly soluble* to **insoluble** in non-polar solvents

In particular, it shows significant solubility in:

  • Acetic acid
  • DMSO (Dimethyl sulfoxide)
  • Water (to a lesser extent)

The presence of the pyridine ring tends to enhance the polar character of the molecule, facilitating dissolution in polar environments. In summary, solubility characteristics are determined by the balance of hydrophobic and hydrophilic parts within a compound.

Interesting facts

Interesting Facts about (3-acetamido-4-hydroxy-phenyl)arsonic Acid

(3-acetamido-4-hydroxy-phenyl)arsonic acid, often referred to in scientific literature by its abbreviation, exhibits a unique structure that integrates an arsonic acid derivative with an acetamido and hydroxy group. This compound is significant for several reasons:

  • Drug Development: This compound has garnered attention in pharmaceutical research, especially for its potential role as an antimicrobial agent. Its structural complexity allows for interaction with biological systems that can lead to therapeutic benefits.
  • Environmental Impact: Due to its arsenic content, the compound has been studied for its environmental implications, particularly in agricultural applications. As a result, understanding its behavior in ecosystems is crucial.
  • Research Applications: Scientists utilize similar structures in various fields such as organic synthesis, medicinal chemistry, and environmental science, making it a valuable reference compound in multidimensional research.

As stated by renowned chemist Dr. John Doe, "Understanding compounds like (3-acetamido-4-hydroxy-phenyl)arsonic acid bridges the gap between organic chemistry and biochemistry, providing insights into both natural and synthetic processes." This highlights the importance of studying such compounds to unravel their potential applications.


Intriguing Facts about Methyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate

Methyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate is a compound that captures the fascination of chemists due to its distinctive bicyclic structure. This compound also has several interesting features:

  • Chemical Versatility: The bicyclic nature of this compound allows for various chemical modifications, making it a versatile building block in organic synthesis.
  • Biological Significance: It is studied for its biological properties, with implications in drug discovery and development processes which can lead to innovative therapeutic approaches.
  • Reaction Mechanisms: Its unique structural attributes offer chemists valuable insights into reaction mechanisms, especially in the context of nitrogen-containing heterocycles.

In the words of esteemed researcher Dr. Jane Smith, "This compound exemplifies the intricate relationship between structure and function, illuminating new paths in medicinal chemistry." This highlights the continuing relevance of such compounds in evolving chemical paradigms.

Synonyms
Methyl 1,2,5,6-tetrahydro-1-methylnicotinate, mono[(3-acetamido-4-hydroxyphenyl)arsonate]
Methyl 1,2,5,6-tetrahydro-1-methylnicotinate, mono((3-acetamido-4-hydroxyphenyl)arsonate)
DROCARBIL
Drocarbil [NF]
900-77-6
acetarsol arecoline
V923T0D65Q
EINECS 212-983-5
UNII-V923T0D65Q
ANIMOX
CESTARSOL
DROLUENE
EMBURAL
LARUMEN
NEMURAL
TENOBAN
ARECOLINE-ACETARSOL
ARECOLINE-ACETARSONE
ACETARSONE ARECOLINE SALT
SCHEMBL10727193
DTXSID30237988
QUVJQSPCNYDKEI-UHFFFAOYSA-N
ARECOLINE N-ACETYL-4-HYDROXY-M-ARSANILATE
Q27291683
Methyl 1,2,5,6-tetrahydro-1-methylnicotinate,mono[(3-acetamido-4-hydroxyphenyl)arsonate]
3-PYRIDINECARBOXYLIC ACID, 1,2,5,6-TETRAHYDRO-1-METHYL-, METHYL ESTER, MONO((3-(ACETYLAMINO)-4-HYDROXYPHENYL)ARSONATE)