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N-Acetylglucosamine 6-phosphate

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Identification
Molecular formula
C8H16NO8P
CAS number
14306-25-3
IUPAC name
[3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl] dihydrogen phosphate
State
State

Under standard conditions (room temperature and pressure), N-Acetylglucosamine 6-phosphate is typically in a solid state.

Melting point (Celsius)
82.50
Melting point (Kelvin)
355.60
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
323.20g/mol
Molar mass
323.2320g/mol
Density
1.7982g/cm3
Appearence

This compound typically appears as a white or off-white crystalline powder. It may also be found in an amorphous form, which is less structured than crystalline forms. However, the precise appearance can vary depending on the sample's purity and specific form (hydrate or anhydrous).

Comment on solubility

Solubility of [3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl] dihydrogen phosphate

The compound [3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl] dihydrogen phosphate, with the chemical formula C8H16NO8P, shows notable solubility characteristics due to its intricate structure.

Understanding its solubility can be approached by considering several key factors:

  • Polarity: The presence of multiple hydroxyl (-OH) groups contributes to the compound's polarity, enhancing its ability to interact with polar solvents such as water.
  • Functional groups: The dihydrogen phosphate group (-H2PO4) is highly soluble in aqueous solutions, facilitating its dissolution in water.
  • Hydrophilic regions: The -NH2 and hydroxyl groups create hydrophilic regions, increasing solubility in polar solvents.
  • Potential for hydrogen bonding: The compound can form hydrogen bonds with water, which enhances its solubility characteristics.

In summary, this compound is expected to display good solubility in water due to its high polarity and ability to engage in hydrogen bonding. As a result, it can be effectively utilized in various aqueous applications, making it a versatile compound in the realm of chemical science.

Interesting facts

Interesting Facts about [3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl] dihydrogen phosphate

This intriguing compound, often abbreviated in the scientific community, holds significance in biochemical research, particularly in the field of nucleotides and their derivatives. Here are some compelling points to consider:

  • Role in Metabolism: Many compounds in this class play essential roles as intermediates in metabolic pathways, connecting various biosynthetic and catabolic processes.
  • Enzymatic Activity: Compounds like this one can interact with enzymes, affecting their stability and activity. This opens avenues for research into enzyme kinetics and inhibition.
  • Structural Complexity: The structural framework of the compound includes a sugar-derived component, indicating its potential involvement in the synthesis of complex biomolecules.
  • Phosphate Group Significance: The presence of a phosphate group suggests a role in energy transfer and storage, reminiscent of adenosine triphosphate (ATP), a crucial energy currency in cells.
  • Therapeutic Potential: Researchers are investigating compounds like this for their potential applications in drug development, particularly targeting metabolic and genetic disorders.

As the renowned chemist Linus Pauling once remarked, "The best way to have a good idea is to have a lot of ideas." This compound exemplifies the creativity and complexity of nature’s design, inviting future explorations in organic and medicinal chemistry.

Overall, the exploration of this molecule provides a glimpse into the dynamic interactions that define biochemical systems and the remarkable potential for innovation in medicinal chemistry.

Synonyms
901851-43-2
N-acetyl-D-hexosamine 1-phosphate
[3-acetylamino-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphosphonic acid
SCHEMBL15334201
CHEBI:52079
NS00015233
2-acetamido-2-deoxy-1-O-phosphonohexopyranose
Q27123159
2-acetamido-2-deoxy-D-hexopyranose 1-(dihydrogen phosphate)