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Dolichyl phosphate

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Identification
Molecular formula
C21H39O9P
CAS number
1260-63-7
IUPAC name
[3-acetamido-5-[3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl] [hydroxy(3,7,11,15,19,23,27,31,35,39,43-undecamethyltetratetraconta-2,6,10,14,18,22,26,30,34,38,42-undecaenoxy)phosphoryl] hydrogen phosphate
State
State

At room temperature, dolichyl phosphate is typically a liquid. This compound may form a viscous liquid, whose properties slightly vary based on the length of the polyisoprene chain.

Melting point (Celsius)
-20.00
Melting point (Kelvin)
253.15
Boiling point (Celsius)
574.00
Boiling point (Kelvin)
847.15
General information
Molecular weight
948.56g/mol
Molar mass
948.5620g/mol
Density
1.0500g/cm3
Appearence

Dolichyl phosphate is typically a colorless or pale yellow liquid. It may appear slightly viscous depending on its state of purity and the length of the polyisoprene chain.

Comment on solubility

Solubility of 3-acetamido-5-[3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl] [hydroxy(3,7,11,15,19,23,27,31,35,39,43-undecamethyltetratetraconta-2,6,10,14,18,22,26,30,34,38,42-undecaenoxy)phosphoryl] hydrogen phosphate (C21H39O9P)

The solubility of this compound is influenced by various factors, reflecting its complex structure and functional groups. Due to the presence of multiple hydroxyl (-OH) groups and a phosphate group, the solubility can vary significantly in different solvents. Here are some key points to consider:

  • Hydrophilicity: The hydroxyl groups enhance water solubility, making it more soluble in polar solvents.
  • Hydrophobic Effects: The undecamethyltetratetraconta-2,6,10,14,18,22,26,30,34,38,42-undecaenoxy group may introduce hydrophobic characteristics, potentially reducing solubility in water.
  • Solvent Dependency: The compound may show varying solubility in different organic solvents; for example, it could be more soluble in ethanol or methanol than in less polar solvents.
  • Temperature Influence: Increased temperature can enhance solubility for many compounds; however, this is not universally applicable.

To summarize, the solubility of this compound is subject to considerable variation based on solvent choice and environmental conditions. Its complex nature suggests that experimentation in various conditions is essential for determining precise solubility characteristics. As stated, "Solubility is key to understanding reactivity and bioavailability," making it a vital area for further exploration.

Interesting facts

Interesting Facts about 3-acetamido-5-[3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl] [hydroxy(3,7,11,15,19,23,27,31,35,39,43-undecamethyltetratetraconta-2,6,10,14,18,22,26,30,34,38,42-undecaenoxy)phosphoryl] hydrogen phosphate

This compound is a fascinating example of complex organic chemistry and illustrates the intricate connections between amino acids, carbohydrates, and phosphates. Here are some interesting aspects of this compound:

  • Structural Complexity: This molecule features multiple alarming functionalities including acetamido groups, hydroxyl groups, and a phosphoryl group, showcasing the intricate design often sought in pharmaceutical chemistry.
  • Biological Importance: Phosphate groups play crucial roles in biological systems, particularly in energy storage and transfer, as seen in ATP (adenosine triphosphate). This compound, with its phosphoryl functionality, may demonstrate similar bioactivity.
  • Potential Applications: Given its structure, the compound may serve as a potential candidate for drug development or as a biochemical probe, assisting in the study of metabolic processes.
  • Chirality: The presence of several stereo-centers in its structure introduces the possibility of chiral molecules, which can drastically influence the biological activity and interactions of the compound.
  • Research Significance: Molecules like this are often studied to understand their roles in biochemistry and medicinal chemistry, laying the groundwork for future innovations in therapeutics.

As we continue to unravel the complexities of chemical compounds, understanding such intricate structures not only fosters our knowledge of molecular interactions but also drives the advancement of new technologies and therapies that can transform lives.