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Iopamidol

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Identification
Molecular formula
C17H22I3N3O8
CAS number
60166-93-0
IUPAC name
3-acetamido-5-[acetyl(methyl)amino]-2,4,6-triiodo-benzoic acid;6-(methylamino)hexane-1,2,3,4,5-pentol
State
State

At room temperature, iopamidol is typically in a solid state as a powder.

Melting point (Celsius)
254.00
Melting point (Kelvin)
527.15
Boiling point (Celsius)
220.00
Boiling point (Kelvin)
493.15
General information
Molecular weight
777.09g/mol
Molar mass
777.0900g/mol
Density
1.4668g/cm3
Appearence

Iopamidol is a white crystalline powder. It is odorless and stable under normal conditions.

Comment on solubility

Solubility of 3-acetamido-5-[acetyl(methyl)amino]-2,4,6-triiodo-benzoic acid; 6-(methylamino)hexane-1,2,3,4,5-pentol

Understanding the solubility of complex chemical compounds can provide insights into their usability and potential applications. For the compound 3-acetamido-5-[acetyl(methyl)amino]-2,4,6-triiodo-benzoic acid; 6-(methylamino)hexane-1,2,3,4,5-pentol, several factors influence its solubility, including:

  • Polar vs. Non-Polar Nature: The presence of multiple polar functional groups in this compound suggests a tendency towards high solubility in polar solvents such as water.
  • Hydrogen Bonding: The ability to form hydrogen bonds due to amino and acetamido groups can enhance solubility in aqueous environments.
  • Iodine Atoms: The tri-iodinated benzoic acid portion may introduce unique solubility characteristics, as halogens can affect dipole interactions.

As a general rule, compounds are more soluble in solvents that have similar polarities. Therefore, this compound is expected to be more soluble in polar solvents compared to non-polar solvents. However, the specific solubility can vary based on other factors such as temperature and the presence of additional solutes.

In summary, while this compound may exhibit reasonable solubility in polar solvents, the influence of its structure and the interactions within various solution environments can lead to complex solubility behaviors.

Interesting facts

Interesting Facts about 3-Acetamido-5-[acetyl(methyl)amino]-2,4,6-triiodo-benzoic acid; 6-(methylamino)hexane-1,2,3,4,5-pentol

This compound showcases an intriguing structure that combines multiple functional groups, making it a unique subject of study in the realm of organic chemistry. Here are some key highlights:

  • Dual Role: This compound exhibits both acidic and basic properties due to its carboxylic acid and amine groups, giving it the ability to participate in a variety of chemical reactions and interactions.
  • Halogenated Benzene: The presence of iodine substituents in the benzene ring plays a critical role in enhancing the compound's activity, especially in medicinal chemistry, where halogenated compounds often exhibit improved biological properties.
  • Polyol Component: The polyol portion (hexane-1,2,3,4,5-pentol) incorporates multiple hydroxyl groups, which can significantly increase solubility in water and influence the overall reactivity of the molecule.
  • Pharmaceutical Potential: Compounds featuring iodine, amine, and amide functionalities are often investigated for their potential antimicrobial and antitumor activities, making this compound of interest in drug discovery.
  • Complex Synthesis: The synthesis of such compounds often requires a multi-step process, involving reactions like acetylation and iodination, which can challenge chemists but also lead to innovative synthetic routes.

Overall, the combination of acetamido, methylamino, and halogenated elements in this compound can lead to fascinating exploration in terms of its chemical reactivity and biological applications. As researchers delve deeper, this compound may unveil new frontiers in medicinal chemistry and materials science.

Synonyms
Isopaque cerebral
DTXSID40274748
18555-27-6
DTXCID80226206