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Iohexol

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Identification
Molecular formula
C19H26I3N3O9
CAS number
66108-95-0
IUPAC name
3-acetamido-5-formamido-2,4,6-triiodo-benzoic acid
State
State

At room temperature, Iohexol is in a solid state. It is commonly used in medical imaging and is available as a solution for injection due to its solubility in water.

Melting point (Celsius)
172.00
Melting point (Kelvin)
445.15
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.00
General information
Molecular weight
821.13g/mol
Molar mass
821.1340g/mol
Density
1.4600g/cm3
Appearence

Iohexol appears as a white crystalline powder. It is visually characterized by its solid form and lack of color.

Comment on solubility

Solubility of 3-acetamido-5-formamido-2,4,6-triiodo-benzoic acid

The solubility of 3-acetamido-5-formamido-2,4,6-triiodo-benzoic acid in various solvents can offer intriguing insights into its behavior and applications. This compound's significant iodo substitutions suggest a level of polarity that can influence its overall solubility characteristics. Here are a few key points regarding its solubility:

  • Water Solubility: The presence of the carboxylic acid group (-COOH) promotes some degree of solubility in water, though the high iodination may hinder it due to increased molecular weight and decreased intermolecular hydrogen bonding.
  • Alcohol Solubility: Solvents like ethanol or methanol may show better solubility due to the ability of these solvents to interact with the polar groups present in the molecule.
  • Organic Solvents: Non-polar organic solvents could exhibit poor solubility for this compound due to its polar functional groups, which are less compatible with non-polar environments.

In summary, while 3-acetamido-5-formamido-2,4,6-triiodo-benzoic acid may have moderate solubility in polar solvents, the extent of its dissolution can vary significantly depending on the solvent choice. Therefore, understanding its solubility is crucial for potential applications in pharmaceuticals or analytical chemistry.

Interesting facts

Interesting Facts about 3-Acetamido-5-formamido-2,4,6-triiodo-benzoic Acid

3-Acetamido-5-formamido-2,4,6-triiodo-benzoic acid is a fascinating compound with important applications and properties that make it noteworthy in the field of chemistry. Here are some interesting facts:

  • Medical Relevance: This compound is often studied for its potential use in radiology, particularly as a contrast agent in imaging techniques, such as X-rays and CT scans. Its ability to absorb X-rays makes it invaluable in enhancing the contrast of images.
  • Halogen Impact: The presence of iodine (as seen in the 'triiodo' part of the name) contributes significantly to the compound’s properties, especially in terms of its reactivity and biological implications. Iodine is known for its ability to create stable complexes, enhancing the compound's utility.
  • Synthetic Pathways: The synthesis of this compound involves multiple steps, often requiring the careful introduction of each functional group. Its complex structure highlights the intricate nature of organic synthesis, making it a subject of interest for students and researchers alike.
  • Colorimetric Applications: Interestingly, compounds like this can also be studied for their colorimetric properties, where changes in color upon interaction with specific substances can be useful in chemical analyses.
  • Research Potential: Ongoing research is examining the broader implications of this compound, including its potential therapeutic uses in drug design and development.

As a compound rich in *functional groups* and *halogen substitutions*, 3-acetamido-5-formamido-2,4,6-triiodo-benzoic acid serves as an exemplary model for studying the intricate relations between molecular structure and function. Its presence in various studies underscores its significance in both academia and industry.

Synonyms
3-Acetamido-5-formamido-2,4,6-triiodobenzoic acid
19719-00-7
BRN 3000961
BENZOIC ACID, 3-ACETAMIDO-5-FORMAMIDO-2,4,6-TRIIODO-
DTXSID00173384
4-14-00-01307 (Beilstein Handbook Reference)
DTXCID6095875
RefChem:327180
3-(Acetylamino)-5-(formylamino)-2,4,6-triiodobenzoic acid