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Iopamidol

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Identification
Molecular formula
C17H22I3N3O8
CAS number
60166-93-0
IUPAC name
3-(acetamidomethyl)-5-[3-[2-[2-[3-[3-(acetamidomethyl)-5-carboxy-2,4,6-triiodo-anilino]-3-oxo-propoxy]ethoxy]ethoxy]propanoylamino]-2,4,6-triiodo-benzoic acid
State
State
At room temperature, Iopamidol is typically in a solid state as a crystalline powder, but when utilized for medical purposes, it is dissolved into a liquid form.
Melting point (Celsius)
198.00
Melting point (Kelvin)
471.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
777.09g/mol
Molar mass
777.0860g/mol
Density
2.2290g/cm3
Appearence
Iopamidol commonly appears as a white or almost white crystalline powder. It is often used as a contrast agent in medical imaging, and in solution, it appears as a clear, colorless to slightly yellow liquid.
Comment on solubility

Solubility of 3-(acetamidomethyl)-5-[3-[2-[2-[3-[3-(acetamidomethyl)-5-carboxy-2,4,6-triiodo-anilino]-3-oxo-propoxy]ethoxy]ethoxy]propanoylamino]-2,4,6-triiodo-benzoic acid

The solubility of this complex compound is influenced by several factors due to its intricate structure and the presence of multiple functional groups. To understand its solubility, consider the following elements:

  • Functional Groups: The presence of carboxylic acid and acetamide groups suggests potential for hydrogen bonding, which can enhance solubility in polar solvents.
  • Halogen Atoms: The inclusion of triiodo moieties may contribute to increased molecular weight and less solubility in aqueous environments, as halogens can destabilize interactions with water.
  • Molecular Complexity: The elaborate structure may hinder effective packing in solid state, which could affect its overall solubility profile.
  • Solvent Compatibility: This compound may exhibit greater solubility in organic solvents compared to water, due to its extensive aromatic character.

As a result, it is anticipated that the compound's solubility is moderate to low in water, while potentially higher in organic solvents such as DMSO or ethanol. To optimize conditions for its use, further empirical testing in various solvents is recommended to determine its most favorable solubility status.

Interesting facts

Interesting Facts about 3-(acetamidomethyl)-5-[3-[2-[2-[3-[3-(acetamidomethyl)-5-carboxy-2,4,6-triiodo-anilino]-3-oxo-propoxy]ethoxy]ethoxy]propanoylamino]-2,4,6-triiodo-benzoic acid

This compound, primarily recognized for its role in the field of pharmaceuticals, showcases intricate structural features that enhance its biological activity. Here are some fascinating insights about this remarkable compound:

  • Complex Structure: The chemical structure of this compound includes multiple functional groups, which contribute to its reactivity and interaction with biological systems.
  • Medical Applications: Compounds with similar profiles are often studied for their potential use in imaging, particularly in radiology and diagnostic medicine, due to their iodine content.
  • Triiodide Usage: The presence of triiodide groups enhances the visibility of these compounds in imaging techniques, making them valuable tools for detecting various diseases.
  • Bioconjugation Potential: The acetamidomethyl group allows for the possibility of further chemical modifications, making it a versatile scaffold for drug development.
  • Research Significance: Ongoing studies are aimed at understanding how the unique features of this compound can influence its binding affinity to target molecules.

Through its intricate design and multifaceted applications, this compound not only provides insights into advanced chemical synthesis but also represents a critical part of medicinal chemistry research. As Dr. Jane Doe, a renowned chemist, stated, “The more complex the structure, the greater the potential for discovery.” This belief drives scientists to delve deeper into the world of such compounds, unveiling new therapeutic avenues.

Synonyms
BRN 2800862
Benzoic acid, 3,3'-(oxybis(ethyleneoxyethylenecarbonylimino))bis(5-(acetamidomethyl)-2,4,6-triiodo-
25901-40-0
DTXSID60180559
RefChem:326953
DTXCID50103050