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Iodixanol

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Identification
Molecular formula
C35H44I6N6O15
CAS number
92339-11-2
IUPAC name
3-(acetamidomethyl)-5-[[7-[3-(acetamidomethyl)-5-carboxy-2,4,6-triiodo-anilino]-7-oxo-heptanoyl]amino]-2,4,6-triiodo-benzoic acid
State
State

At room temperature, iodixanol is typically in the form of a solid as a crystalline powder.

Melting point (Celsius)
133.00
Melting point (Kelvin)
406.15
Boiling point (Celsius)
118.50
Boiling point (Kelvin)
391.65
General information
Molecular weight
1550.23g/mol
Molar mass
1 550.2320g/mol
Density
1.6200g/cm3
Appearence

Iodixanol appears as a white to off-white crystalline powder. It is used widely in medical imaging due to its iodinated nature, providing contrast in radiographic tests.

Comment on solubility

Solubility of 3-(acetamidomethyl)-5-[[7-[3-(acetamidomethyl)-5-carboxy-2,4,6-triiodo-anilino]-7-oxo-heptanoyl]amino]-2,4,6-triiodo-benzoic acid

The compound 3-(acetamidomethyl)-5-[[7-[3-(acetamidomethyl)-5-carboxy-2,4,6-triiodo-anilino]-7-oxo-heptanoyl]amino]-2,4,6-triiodo-benzoic acid showcases distinct solubility characteristics, which can be essential for its application in various fields. Here are some key points to consider:

  • Solubility Category: Given its complex structure, this compound is expected to exhibit limited solubility in non-polar solvents.
  • Polar Solvents: It is likely to dissolve better in polar solvents such as water or alcohol due to the presence of the acid and amide functional groups, which can form hydrogen bonds.
  • Factors Influencing Solubility: The solubility may also be influenced by the compound's pH, temperature, and the presence of other ionic species in solution.
  • Practical Implications: Understanding the solubility behavior is crucial for its potential uses in pharmaceuticals, where solubility can impact bioavailability and therapeutic efficacy.

In conclusion, the solubility of this compound is a multifaceted aspect, driven by its intricate chemical structure and the balance of polar and non-polar features. As with many chemical compounds, experimentation and specific conditions will ultimately determine its solubility profile.

Interesting facts

Interesting Facts About 3-(Acetamidomethyl)-5-[[7-[3-(acetamidomethyl)-5-carboxy-2,4,6-triiodo-anilino]-7-oxo-heptanoyl]amino]-2,4,6-triiodo-benzoic Acid

This compound, with a complex structure, is notable for its rich incorporation of iodine atoms, which significantly enhances its biological and chemical properties. Here are some engaging insights about this fascinating compound:

  • Diagnostic Imaging: The presence of triiodinated groups makes this compound highly useful in medical imaging, particularly in computed tomography (CT scans) due to the contrast enhancement properties of iodine.
  • Anticancer Research: Being part of a family of iodinated benzoic acid derivatives, this compound is being investigated for its potential anticancer properties. The combination of the triiodinated aniline and heptanoyl functionalities allows for interactions that could inhibit tumor growth.
  • Structure-Activity Relationship (SAR): The intricate arrangement of the acetamidomethyl, carboxy, and triiodo groups is pivotal in the study of SAR, helping scientists design better therapeutic agents by understanding how structure influences activity.
  • Multifunctionality: The diverse functional groups present in the compound allow for multi-targeting strategies in drug design, enabling the compound to interact with various biomolecules, which could enhance its efficacy.
  • Research Applications: This compound's complexity serves as a great subject in graduate studies, offering students rich material for exploring organic synthesis, pharmacology, and biochemical interactions.

In summary, 3-(acetamidomethyl)-5-[[7-[3-(acetamidomethyl)-5-carboxy-2,4,6-triiodo-anilino]-7-oxo-heptanoyl]amino]-2,4,6-triiodo-benzoic acid is a prime example of how organic chemistry can lead to the development of compounds with significant biomedical applications. As researchers continue to explore its potential, it stands as a testament to the innovative possibilities within the field of medicinal chemistry.

Synonyms
BRN 2800649
BENZOIC ACID, 3,3'-(PIMELOYLDIIMINO)BIS(5-(ACETAMIDOMETHYL)-2,4,6-TRIIODO-
26280-73-9
DTXSID50180907
3,3'-(Heptanedioyldiimino)bis(5-(acetamidomethyl)-2,4,6-triiodobenzoic acid)
RefChem:326957
DTXCID50103398