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Iodixanol

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Identification
Molecular formula
C35H44I6N6O15
CAS number
92339-11-2
IUPAC name
3-(acetamidomethyl)-5-[[8-[3-(acetamidomethyl)-5-carboxy-2,4,6-triiodo-anilino]-8-oxo-octanoyl]amino]-2,4,6-triiodo-benzoic acid
State
State

Iodixanol is typically in a solid state at room temperature. However, it is often used in a liquid form when dissolved in a suitable solvent for use in medical imaging as a contrast agent.

Melting point (Celsius)
250.00
Melting point (Kelvin)
523.15
Boiling point (Celsius)
275.50
Boiling point (Kelvin)
548.70
General information
Molecular weight
1550.24g/mol
Molar mass
0.0000g/mol
Density
1.6100g/cm3
Appearence

Iodixanol typically appears as a white or off-white powder or crystalline substance. It may also be encountered in solution form for medical imaging purposes. As a dry compound, it remains a solid at room temperature.

Comment on solubility

Solubility of 3-(acetamidomethyl)-5-[[8-[3-(acetamidomethyl)-5-carboxy-2,4,6-triiodo-anilino]-8-oxo-octanoyl]amino]-2,4,6-triiodo-benzoic acid

The solubility of this complex compound is influenced by several factors due to its intricate structure. Generally, the presence of multiple functional groups, such as acetamido and carboxy groups, suggests the potential for varied solubility in polar solvents. Here are some key points to consider:

  • Hydrophilicity: The acetamido and carboxylic acid groups contribute to hydrophilic characteristics, increasing the likelihood of solubility in water.
  • Hydrophobic interactions: Conversely, the presence of triiodo substituents may create hydrophobic areas, which could hinder solubility in aqueous environments.
  • Solvent Effects: Solubility may vary significantly between solvents. For instance, the compound may exhibit higher solubility in dimethyl sulfoxide (DMSO) or other polar aprotic solvents compared to water.
  • Influence of Temperature: As with many compounds, increasing temperature commonly enhances solubility, potentially allowing for greater dissolution in solvents.

Overall, while predictions can be made regarding the solubility of this compound, it is advisable to conduct experimental assessments for precise quantification. The unique structure dictates that solubility will be contingent upon a balance of hydrophilic and hydrophobic interactions in the chosen solvent system.

Interesting facts

Interesting Facts about 3-(Acetamidomethyl)-5-[[8-[3-(acetamidomethyl)-5-carboxy-2,4,6-triiodo-anilino]-8-oxo-octanoyl]amino]-2,4,6-triiodo-benzoic acid

This compound, a complex organic molecule with multiple functional groups, belongs to the realm of iodinated benzoic acids. Its intricate structure offers unique characteristics and fascinating applications that make it of great interest to the scientific community.

Molecular Features

  • Iodine-rich Structure: With three iodine atoms, this compound is particularly significant in medical imaging, especially in techniques like X-ray computed tomography (CT) where iodinated compounds serve as contrast agents.
  • Dual Functionality: The presence of both acetamidomethyl groups and carboxylic acid functionalities suggests this compound might have dual roles in biochemical pathways, potentially acting as both a precursor and a reagent.
  • Amine Groups: The amine groups within its structure can increase its solubility in biological systems, making this compound ripe for pharmaceutical studies.

Applications in Medicine

The unique arrangement of atoms and functional groups in this compound may enable its use in various medical applications, including:

  • Diagnostic Imaging: Its distinct iodine content can significantly aid in enhancing image contrast during diagnostic procedures.
  • Potential Drug Development: With properties that make it suitable for biological interaction, this compound could be a candidate for new therapeutics aimed at certain diseases.

Scientific Significance

Researchers often find such complex compounds compelling due to their multifaceted nature:

  • They can serve as models for studying biochemical interactions due to their reactive functional groups.
  • Understanding the behavior of compounds like this helps to pave the way for advancements in both materials science and medicinal chemistry.

In conclusion, 3-(acetamidomethyl)-5-[[8-[3-(acetamidomethyl)-5-carboxy-2,4,6-triiodo-anilino]-8-oxo-octanoyl]amino]-2,4,6-triiodo-benzoic acid represents a fascinating intersection of organic chemistry and applied sciences, with promising implications that are yet to be fully explored. Its continuing study could lead to breakthroughs not only in imaging technologies but also potentially in novel therapeutic applications.

Synonyms
BRN 2800657
BENZOIC ACID, 3,3'-(SUBEROYLDIIMINO)BIS(5-(ACETAMIDOMETHYL)-2,4,6-TRIIODO-
25901-34-2
DTXSID60180554
3,3'-(Suberoyldiimino)bis(5-(acetamidomethyl)-2,4,6-triiodobenzoic acid)
RefChem:326965
DTXCID00103045