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Cefaclor

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Identification
Molecular formula
C15H14ClN3O4S
CAS number
53994-73-3
IUPAC name
3-(acetoxymethyl)-7-[(5-amino-5-carboxy-pentanoyl)amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
State
State

Cefaclor exists as a solid at room temperature.

Melting point (Celsius)
83.00
Melting point (Kelvin)
356.00
Boiling point (Celsius)
220.00
Boiling point (Kelvin)
493.00
General information
Molecular weight
368.96g/mol
Molar mass
368.9560g/mol
Density
1.4300g/cm3
Appearence

Cefaclor is typically a white to off-white crystalline powder. It is usually odorless or may have a faint odor.

Comment on solubility

Solubility of 3-(acetoxymethyl)-7-[(5-amino-5-carboxy-pentanoyl)amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate (C15H14ClN3O4S)

The solubility of the compound 3-(acetoxymethyl)-7-[(5-amino-5-carboxy-pentanoyl)amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate is influenced by several factors, including its molecular structure and the presence of various functional groups. Here are some key points regarding its solubility:

  • Polar Functional Groups: The presence of carboxylate (-COO-) and amine (-NH2) groups typically enhances solubility in polar solvents such as water.
  • Hydrophobic Regions: However, the significant hydrophobic structure of the bicyclic system may hinder solubility, leading to a complex relationship with various solvents.
  • Solvent Specificity: This compound may exhibit better solubility in organic solvents like dimethyl sulfoxide (DMSO) or methanol compared to water.
  • pH Dependency: The solubility could also be pH-dependent, particularly due to the ionizable groups, which may become protonated or deprotonated under different pH conditions.

In summary, while the compound has groups that promote solubility in polar solvents, its overall solubility can vary significantly based on the chosen solvent and environmental conditions. Understanding these interactions can be crucial for applications such as drug formulation and material science.

Interesting facts

Interesting Facts about 3-(Acetoxymethyl)-7-[(5-Amino-5-carboxy-pentanoyl)amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

This complex compound represents a fascinating intersection of chemistry and pharmacology. Here are some intriguing insights about its structure and potential applications:

  • Multifunctionality: The presence of both amino and carboxyl functional groups indicates potential reactivity, making this compound a candidate for further modifications and applications in medicinal chemistry.
  • Bicyclic Structure: Its unique bicyclic skeleton (specifically, a thia-azabicyclo structure) is noteworthy. Such frameworks often exhibit biological activity and might serve as scaffolds for drug development.
  • Antibiotic Potential: Compounds with similar structures have been explored for their antibiotic properties, especially against resistant bacterial strains, which highlights the ongoing need for innovative medicinal compounds.
  • Reaction Mechanism: The acetoxymethyl group may modulate reactivity during synthesis, influencing the mechanism of action upon reaching its biological target. This can be crucial in drug design for optimizing efficacy.

The compound's intricate design embodies the creative and exploratory spirit of modern chemistry. As we continue to research its properties and utilities, the role of such compounds in addressing health challenges, including antimicrobial resistance, becomes increasingly significant.

In the words of renowned chemist Linus Pauling, “The best way to have a good idea is to have lots of ideas.” As such, every compound studied opens new avenues for research and discovery.