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Cefotaxime

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Identification
Molecular formula
C16H17N5O7S1
CAS number
63527-52-6
IUPAC name
3-(acetoxymethyl)-7-[(5-amino-5-carboxy-pentanoyl)amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
State
State

Cefotaxime is in solid state at room temperature, generally supplied as a powder for reconstitution to an injectable form.

Melting point (Celsius)
155.00
Melting point (Kelvin)
428.15
Boiling point (Celsius)
313.00
Boiling point (Kelvin)
586.15
General information
Molecular weight
455.47g/mol
Molar mass
455.4660g/mol
Density
1.3000g/cm3
Appearence

Cefotaxime is typically a white to slightly yellowish crystalline powder. It is often used in its sodium salt form, cefotaxime sodium, which is more stable and soluble.

Comment on solubility

Solubility of 3-(acetoxymethyl)-7-[(5-amino-5-carboxy-pentanoyl)amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

The solubility of the compound C16H17N5O7S1 can be quite complex due to its intricate structure and functional groups. Here are some key points regarding its solubility:

  • Polarity: The presence of multiple functional groups such as carboxylic acids and amines suggests that the compound is likely polar, which can enhance its solubility in polar solvents like water.
  • Hydrogen Bonding: The amino and carboxyl moieties can engage in hydrogen bonding, further facilitating solubility in aqueous environments.
  • pH Dependence: The ionization of the carboxylic acid groups may vary with pH, potentially affecting its solubility. In acidic conditions, these groups may remain protonated, while in neutral or basic conditions, they are likely to deprotonate and increase solubility.
  • Magnitude of Solubility: While exact solubility values are not readily available, such compounds generally exhibit moderate to high solubility in biological fluids due to their functional groups.

In summary, the overall solubility of C16H17N5O7S1 can be characterized by its polarized nature and functional group interactions, making it amenable to solubility studies in various solvent environments. Understanding these factors is crucial for predicting behavior in biological systems and potential applications in pharmaceuticals.

Interesting facts

Interesting Facts about 3-(Acetoxymethyl)-7-[(5-amino-5-carboxy-pentanoyl)amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid

This complex compound belongs to a class of molecules known for their intriguing structural and functional characteristics. Commonly used in pharmacological studies, it showcases the fascinating intersection of chemistry and biology. Here are some noteworthy aspects:

  • Structural Complexity: The compound features a bicyclic structure that contributes to its unique biological activity, making it a subject of interest for drug development.
  • Functional Groups: With multiple functional groups, including an amino group and a carboxylic acid, this compound demonstrates the versatility in chemical reactivity, paving the way for diverse chemical transformations.
  • Pharmaceutical Relevance: Compounds of this nature are often explored for their potential as therapeutic agents, exhibiting antibacterial and antiviral properties that are valuable in treating various diseases.
  • Research Impact: As a specialized compound, it often appears in scientific literature where researchers analyze its efficacy, mechanisms of action, and potential therapeutic applications.
  • Synthesis Challenges: The synthesis of such intricate molecules often requires advanced techniques and innovative strategies, making it an excellent subject of practice for organic chemists.

The study of this compound not only enhances our understanding of chemical behavior but also contributes to the ongoing quest for new medicinal therapies. As highlighted by chemists, "Every complex structure tells a story waiting to be unraveled." With ongoing research, the full potential of this compound is still being explored.

Synonyms
Cephalosporine
11111-12-9
3-(Acetyloxymethyl)-7-[(5-amino-5-carboxypentanoyl)amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CHEMBL1624196
HOKIDJSKDBPKTQ-UHFFFAOYSA-N
NS00079152