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Cefaclor

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Identification
Molecular formula
C15H14ClN3O4S
CAS number
53994-73-3
IUPAC name
3-(acetoxymethyl)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
State
State

At room temperature, cefaclor is a solid. It is generally supplied in powder form which can be reconstituted to make oral suspensions.

Melting point (Celsius)
196.00
Melting point (Kelvin)
469.15
Boiling point (Celsius)
650.00
Boiling point (Kelvin)
923.15
General information
Molecular weight
368.39g/mol
Molar mass
368.3880g/mol
Density
1.5400g/cm3
Appearence

Cefaclor typically appears as a white to off-white crystalline powder. It is generally odorless and has a slightly bitter taste.

Comment on solubility

Solubility of 3-(acetoxymethyl)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

The solubility of 3-(acetoxymethyl)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid is an important aspect to consider when evaluating its applications and effectiveness in various environments. Here are some key points to note:

  • Polarity: The presence of polar functional groups such as the amino and carboxylic acid moieties generally enhances its solubility in polar solvents, especially water.
  • Solvent Compatibility: Due to the molecular structure, this compound may exhibit variable solubility depending on the solvent used. Specific solvents that can solvate the functional groups may lead to better solubility.
  • pH Dependence: The solubility of this compound can also be affected by the pH of the solution. Under acidic conditions, the carboxylic group may remain protonated, which could prevent effective solubility.
  • Temperature Influence: Increased temperature typically results in enhanced solubility for many organic compounds, and this compound might follow the same trend.

In summary, while various factors influence the solubility of this compound, emphasis must be placed on its polar characteristics, solvent selection, solution pH, and temperature to thoroughly understand its behavior in different environments. As you explore its solubility, remember that "an understanding of solubility helps unlock a compound's potential." Thus, thorough testing is essential for comprehensive insights.

Interesting facts

Interesting Facts about 3-(Acetoxymethyl)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid

This intriguing compound, often referred to by its more common name in various biochemical circles, embodies a unique structural complexity that is fascinating to both chemists and students alike. Its distinct bicyclic framework presents an excellent opportunity for discussions on molecular geometry and stereochemistry.

Key Highlights:

  • Structural Complexity: This compound features a thiazole ring, which plays a critical role in the pharmacological activity of numerous therapeutic agents.
  • Antibiotic Potential: Compounds with similar structural motifs have been investigated for their abilities to act as antibiotics, showcasing the link between structure and biological function.
  • Formative Research: It is often a subject of research related to antibiotic resistance, shedding light on how modifications in chemical structures can alter biological interactions.
  • Versatility: The presence of the acetoxymethyl group highlights the versatility of this compound, enabling chemists to explore varied synthetic pathways and reactivity.

Applications in Science:

Researchers continue to study this compound due to its potential applications in pharmaceutical chemistry, particularly in the development of new drugs that combat resistant bacterial strains. As a result, understanding its chemical properties can lead to breakthroughs in medical treatments.

In the realm of synthetic chemistry, the compound serves as a useful scaffold for the creation of other biologically active molecules, making it a valuable point of interest for those studying organic synthesis. The intricate balance between its chemical structure and reactivity offers a rich vein of exploration for aspiring chemists.

In conclusion, 3-(acetoxymethyl)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid stands as a testament to the complexity and beauty of chemical compounds, inspiring both passion and curiosity in the field of chemistry.

Synonyms
3-[(Acetyloxy)methyl]-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
108260-00-0
3-(acetyloxymethyl)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
3-(acetoxymethyl)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
68090-55-1
SR-01000317524
SCHEMBL7514855
CHEMBL1161449
DTXSID20859557
(6r)-3-(Acetoxymethyl)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
STK397072
AKOS000300349
AKOS022060452
SB67304
(7R,7aR)-3-(acetyloxymethyl)-7-amino-6-oxo-2H,7H-azetidino[2,1-b]1,3-thiazine- 4-carboxylic acid
AS-44373
PD014029
SY012906
EN300-296214
SR-01000317524-2
3-acetoxymethyl-7-amino-8-oxo-5-thia-1-aza-bicyclo[
3-[(acetyloxy)methyl]-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2carboxylic acid
3-[(acetyloxy)methyl]-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2ene-2carboxylic acid
3-Acetoxymethyl-7-amino-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid
3-acetyloxymethyl-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
3-acetyloxymethyl-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2carboxylic acid
3[(acetyloxy)methyl]-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
(6R,7R)-3-(acetoxymethyl)-7-azaniumyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
3-[(acetyloxy)-methyl]-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
3-[(acetyloxy)-methyl]-7-amino-8-oxo-5-thia-1azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
3-[(acetyloxy)methyl] -7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2- ene-2-carboxylic acid
3-[(acetyloxy)methyl]-7-amino-8-oxo-5-thia-1 -azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
3-[(acetyloxy)methyl]-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0 ]oct-2-ene-2-carboxylic acid
3-[(acetyloxy)methyl]-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]-oct-2-ene-2-carboxylic acid
3-[(Acetyloxy)methyl]-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid #
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-amino-8-oxo-, (6R-trans)-