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Cefotetan

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Identification
Molecular formula
C17H17N7O8S2
CAS number
69712-56-7
IUPAC name
3-(acetoxymethyl)-8-oxo-7-[[2-(2-thienyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;N1,N4-dimethylcyclohexane-1,4-diamine
State
State

At room temperature, cefotetan is typically in a solid state. As a crystalline powder, it is primarily used in its reconstituted form for medical purposes. The compound is stable under standard conditions but should be handled with care as it is sensitive to humidity.

Melting point (Celsius)
210.00
Melting point (Kelvin)
483.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
576.64g/mol
Molar mass
576.6390g/mol
Density
1.5000g/cm3
Appearence

Cefotetan typically appears as a white to off-white crystalline powder. This sterile compound is used in its powder form for preparation into injectable solutions. It has no odor and is hygroscopic, meaning it can absorb moisture from the environment fairly easily.

Comment on solubility

Solubility of 3-(acetoxymethyl)-8-oxo-7-[[2-(2-thienyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; N1,N4-dimethylcyclohexane-1,4-diamine

The solubility of complex organic compounds like 3-(acetoxymethyl)-8-oxo-7-[[2-(2-thienyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid combined with N1,N4-dimethylcyclohexane-1,4-diamine can be influenced by several factors, including their specific structural features and the presence of functional groups. Here are some key points regarding their solubility:

  • Polarity: The presence of polar functional groups (such as carboxylic acid and acetoxy) can contribute to increased solubility in polar solvents like water.
  • Hydrogen bonding: The ability to form hydrogen bonds with solvents can enhance solubility. For instance, carboxylic acids can engage in hydrogen bonding with water.
  • Size and steric hindrance: Larger, bulky groups can impede solubility through steric hindrance, potentially leading to lower solubility in certain conditions.
  • Compatibility: The overall molecular structure, including its hydrophilic and hydrophobic sections, can determine compatibility with solvents.

As a general observation, compounds with such intricate structures might exhibit variable solubility in different media. Thus, it is essential to conduct specific solubility tests in solvents ranging from aqueous to organic to gauge their behavior accurately.

Overall, understanding solubility is crucial for predicting the behavior of these compounds in various chemical environments, and further studies may be necessary to elucidate their properties comprehensively.

Interesting facts

Interesting Facts about 3-(Acetoxymethyl)-8-oxo-7-[[2-(2-thienyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; N1,N4-Dimethylcyclohexane-1,4-diamine

This complex compound is an intriguing example of how diverse chemical structures can lead to unique biological activities. Here are some captivating facts:

  • Medicinal Chemistry: Compounds like this one often play essential roles in medicinal chemistry, particularly in the development of new antibiotics and pharmaceuticals. Scientists are continually exploring its potential therapeutic effects.
  • Structural Features: The combination of bicyclic structures with thiazole and thienyl rings presents significant versatility in its reactivity and binding sites, potentially allowing for diverse interactions with biological targets.
  • Research Studies: Ongoing research into compounds that share similar structural motifs has yielded promising findings in areas such as cancer treatment and anti-inflammatory therapies.
  • Complex Synthesis: The synthetic pathway leading to this compound might require multiple steps and conditions, showcasing the intricacy of organic synthesis that chemists must navigate.
  • Potential Applications: Beyond medicinal uses, compounds like this are often explored for their properties in agrochemicals, material science, and as catalysts in various chemical reactions.

Overall, this compound represents the fascinating intersection of organic chemistry and pharmaceutical development, inspiring future research and innovations in the field. As we delve deeper into its properties, we uncover layers of complexity that are foundational to understanding biochemical interactions.