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Cefonicid

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Identification
Molecular formula
C18H18N6O8S3
CAS number
61270-58-4
IUPAC name
3-(acetoxymethyl)-8-oxo-7-[[2-(4-pyridylsulfanyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
State
State

Cefonicid sodium is typically found as a solid at room temperature when in its pure form.

Melting point (Celsius)
212.00
Melting point (Kelvin)
485.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
585.65g/mol
Molar mass
585.6350g/mol
Density
1.7300g/cm3
Appearence

Cefonicid sodium appears as a white to off-white powder suitable for parenteral use. It is soluble in water, slightly soluble in methanol, and insoluble in most organic solvents.

Comment on solubility

Solubility of 3-(acetoxymethyl)-8-oxo-7-[[2-(4-pyridylsulfanyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

The solubility of the compound with the formula C18H18N6O8S3 reveals some fascinating characteristics. Due to its complex structure, solubility can be influenced by various factors:

  • Polarity: The presence of multiple functional groups, including acetoxy and carboxylic acid moieties, contributes to a mix of polar and non-polar characteristics.
  • Hydrogen Bonding: The carboxylic acid component may facilitate hydrogen bonding, enhancing solubility in polar solvents like water.
  • Sulfur Substitution: The thiol (sulfur) groups can affect solubility and reactivity, potentially increasing solubility in certain organic solvents.
  • Pyridine Group: The aromatic nature of the pyridine ring can also interact favorably with organic solvents, promoting solubility in non-polar environments.

In general, while this compound may exhibit moderate solubility in polar solvents due to its polar functional groups, it might also demonstrate reasonable compatibility with certain non-polar organic solvents due to its aromatic and sulfur content.

As with many complex chemical structures, the exact solubility will often depend on factors such as temperature and solvent composition, making it crucial to conduct specific solubility tests for practical applications.

Interesting facts

Interesting Facts about 3-(Acetoxymethyl)-8-oxo-7-[[2-(4-pyridylsulfanyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

This fascinating compound holds particular significance in the field of medicinal chemistry and drug design. Here are some noteworthy points about it:

  • Structural Complexity: This compound features a unique bicyclic structure, incorporating sulfur and nitrogen atoms, which contributes to its diverse biological activities.
  • Bioactivity: The various functional groups suggest that this compound may possess antibiotic properties, making it a candidate for further research in antimicrobial therapies.
  • Pyridylsulfanyl Moiety: The presence of a pyridylsulfanyl group enhances its interaction with biological systems, possibly improving its efficacy and target specificity in therapeutic applications.
  • Potential Applications: Its structural characteristics indicate potential uses in treating various conditions, leading to new treatments in infectious diseases.
  • Research Opportunities: The complexity of the compound presents numerous opportunities for synthetic chemists to discover new derivatives and analogues that may have improved properties.

As Dr. Marie Curie once said, “In science, we must be interested in things, not in persons.” This compound exemplifies the importance of chemical research in understanding and embracing new molecular characteristics that can lead to groundbreaking innovations in medicine. The exploration of 3-(acetoxymethyl)-8-oxo-7-[[2-(4-pyridylsulfanyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid could very well lead to new horizons in pharmaceuticals.

Synonyms
cephaprin
1205565-31-6
SCHEMBL8194062
CHEMBL1161453
DTXSID40860266
BCP18351
NCI60_001503
NS00003470
Cephapirin; Cefapirine;BL P 1322;BL-P 1322;BLP 1322
3-[(Acetyloxy)methyl]-8-oxo-7-[[2-(4-pyridinylthio)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid