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3-acetyl-1,3-benzoxazol-2-one

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Identification
Molecular formula
C9H7NO3
CAS number
696-23-1
IUPAC name
3-acetyl-1,3-benzoxazol-2-one
State
State

At room temperature, 3-acetyl-1,3-benzoxazol-2-one is typically in a solid state. It is usually stored in a dry, well-ventilated area to maintain its stability and prevent any moisture uptake.

Melting point (Celsius)
162.00
Melting point (Kelvin)
435.15
Boiling point (Celsius)
348.00
Boiling point (Kelvin)
621.15
General information
Molecular weight
177.16g/mol
Molar mass
177.1630g/mol
Density
1.3297g/cm3
Appearence

3-acetyl-1,3-benzoxazol-2-one appears as a crystalline solid. It can range from colorless to off-white in appearance, depending on the purity and specific conditions of synthesis. The crystalline structure and fine particulate nature can be observed upon close examination.

Comment on solubility

Solubility of 3-acetyl-1,3-benzoxazol-2-one

The solubility of 3-acetyl-1,3-benzoxazol-2-one, also known as ABO, can vary significantly depending on the solvent used. This compound exhibits certain characteristics that influence its solubility:

  • Polarity: Being a heterocyclic compound, the polarity of 3-acetyl-1,3-benzoxazol-2-one plays a crucial role. It is moderately polar, which allows it to dissolve in polar solvents.
  • Alcohol Solubility: It is generally soluble in common alcohols such as ethanol and methanol, making these solvents suitable for various reactions and applications.
  • Non-Polar Solvents: Interestingly, the solubility in non-polar solvents, like hexane or benzene, is quite limited due to the compound's structural features that promote interactions with polar solvents.
  • Temperature Dependence: The solubility can also change with temperature; as with many organic compounds, higher temperatures can lead to increased solubility.

In summary, when working with 3-acetyl-1,3-benzoxazol-2-one, it is crucial to consider the choice of solvent, as the solubility properties significantly influence its behavior in chemical reactions. As a guiding principle, remember:

"The right solvent can make or break the effectiveness of a compound."
Interesting facts

Exploring 3-acetyl-1,3-benzoxazol-2-one

3-acetyl-1,3-benzoxazol-2-one is a fascinating compound with diverse applications in both chemistry and pharmacology. Known for its unique structure, this compound is characterized by a benzoxazole ring fused with an acetyl group, which contributes to its intriguing reactivity and properties.

Key Features of 3-acetyl-1,3-benzoxazol-2-one

  • Fluorescent Properties: Due to its conjugated system, 3-acetyl-1,3-benzoxazol-2-one exhibits fluorescence, making it useful in various applications such as fluorescent probes in biological systems.
  • Pharmacological Potential: This compound has garnered interest in medicinal chemistry due to its bioactivity, showing potential anti-inflammatory and antimicrobial properties in preliminary studies.
  • Synthesis: Its synthesis involves the condensation of substituted anilines with a carboxylic acid derivative, often leading to efficient one-pot reactions that are appealing to chemists for laboratory practice.

Furthermore, the study of 3-acetyl-1,3-benzoxazol-2-one has implications in the development of new synthetic methodologies. Research may focus on enhancing its biological activity and creating derivatives with optimized properties. As the field of pharmaceuticals evolves, compounds like 3-acetyl-1,3-benzoxazol-2-one remind us of the intricate connections between chemical structure and biological function.

As the famous chemist Linus Pauling once said, "The science of chemistry is the science of change." The ongoing exploration of compounds like 3-acetyl-1,3-benzoxazol-2-one exemplifies this change, driving innovation in both synthetic chemistry and drug discovery.

Synonyms
24963-28-8
2-BENZOXAZOLINONE, 3-ACETYL-
DTXSID70179671
RefChem:1067252
3-Acetyl-2(3H)-benzoxazolone
DTXCID30102162
3-Acetyl-2-benzoxazolinone
3-Acetylbenzo[d]oxazol-2(3H)-one
3-acetyl-1,3-benzoxazol-2-one
2(3H)-Benzoxazolone, 3-acetyl-
3-acetyl-2,3-dihydro-1,3-benzoxazol-2-one
MFCD00092623
3-acetyl-2-oxo-3-hydrobenzoxazole
N-Acetylbenzoxazolone
BRN 0151196
3-Acetylobenzoksazolinon-2 [Polish]
3-Acetylobenzoksazolinon-2
3-Acetyl-3H-benzooxazol-2-one
3-acetylbenzoxazolinone
N-acetyl-2-benzoxazolone
TimTec1_006660
4-27-00-02680 (Beilstein Handbook Reference)
MLS001048968
SCHEMBL7525629
CHEMBL1817730
KIIQPJPWSJBTGN-UHFFFAOYSA-N
HMS1552O16
HMS2746H07
SBB012375
STK793047
AKOS005609133
3-acetyl-1,3-benzoxazol-2(3H)-one
AC-18169
SMR000146872
ST058452
DB-046590
CS-0336223
EU-0000403
963A288
SR-01000391631
SR-01000391631-1