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Dihydrocoumarin derivative

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Identification
Molecular formula
C12H10O3
CAS number
521-09-1
IUPAC name
3-acetyl-7-methyl-chromen-2-one
State
State

Solid at room temperature.

Melting point (Celsius)
113.00
Melting point (Kelvin)
386.15
Boiling point (Celsius)
320.00
Boiling point (Kelvin)
593.15
General information
Molecular weight
202.22g/mol
Molar mass
202.2170g/mol
Density
1.1000g/cm3
Appearence

A pale yellow crystalline solid with a characteristic odor.

Comment on solubility

Solubility of 3-acetyl-7-methyl-chromen-2-one

3-acetyl-7-methyl-chromen-2-one, also known as a flavonoid compound, exhibits interesting solubility characteristics that are essential for its applications in various fields, such as pharmaceuticals and natural products. The solubility of this compound can be affected by several factors:

  • Polar vs. Nonpolar Solvents: This compound is likely to be more soluble in organic solvents, such as ethanol or acetone, rather than in water due to its nonpolar characteristics.
  • Temperature: Increased temperature can enhance solubility, allowing for a higher dissolution rate of 3-acetyl-7-methyl-chromen-2-one in appropriate solvents.
  • pH Levels: The solubility profile might vary with pH; compounds with acidic or basic functionalities can undergo ionization, which could affect their solubility.

In practical terms, it has been observed that:

  • The compound may dissolve well in dimethyl sulfoxide (DMSO), a common solvent used in biological studies.
  • Its solubility in water is limited, which often necessitates the use of solvent mixtures when considering biological applications.

As a note on its application, due to its moderate solubility, 3-acetyl-7-methyl-chromen-2-one is frequently utilized in formulations where oily or organic environments are present, allowing it to retain its efficacy as a bioactive compound.

Interesting facts

Interesting Facts about 3-acetyl-7-methyl-chromen-2-one

3-acetyl-7-methyl-chromen-2-one, commonly known in scientific circles as a flavonoid compound, is part of a larger group known for their diverse range of biological activities. Here are some fascinating insights about this compound:

  • Flavonoid Family: This compound belongs to the flavone class of flavonoids, which are polyphenolic compounds widely distributed in the plant kingdom. They play an essential role in plant pigmentation and UV filtration.
  • Biological Significance: Numerous studies have highlighted the potential health benefits associated with flavonoids, including antioxidant, anti-inflammatory, and antimicrobial properties. Some research suggests that they may contribute to cardiovascular health as well.
  • Synthetic Pathways: The synthesis of 3-acetyl-7-methyl-chromen-2-one is a subject of interest in organic chemistry. Various synthetic routes exist, providing valuable insights into chemical reactions and methodologies.
  • Natural Occurrence: Similar compounds can be found in various plants, particularly in fruits, vegetables, and herbs, contributing to both their flavor and health benefits.
  • Color and Aesthetics: Flavonoids, including this compound, often contribute to the vibrant colors observed in fruits and flowers, making them not only scientifically interesting but also visually appealing in nature.

As a student or scientist, delving into the world of 3-acetyl-7-methyl-chromen-2-one opens up a treasure trove of opportunities for research and exploration. Its multifaceted properties reveal the intricate connections between chemistry and the natural world.

Synonyms
20280-93-7
3-Acetyl-7-methylcoumarin
COUMARIN, 3-ACETYL-7-METHYL-
BRN 0160620
DTXSID80174137
4-17-00-06297 (Beilstein Handbook Reference)
DTXCID7096628
RefChem:334401
3-acetyl-7-methyl-2H-chromen-2-one
3-acetyl-7-methylchromen-2-one
MFCD01731853
2H-1-Benzopyran-2-one, 3-acetyl-7-methyl-
SCHEMBL12611180
3-acetyl-7-methyl-chromen-2-one
ALBB-008115
STK505102
AKOS002679511
LS-02896
H24727