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Acridine Orange

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Identification
Molecular formula
C17H19N3Cl2
CAS number
494-38-2
IUPAC name
3-(acridin-9-ylammonio)propyl-dimethyl-ammonium;dichloride
State
State

At room temperature, it is typically in a solid state, often found as a powder. In laboratory settings, it is usually dissolved in a solvent such as water or ethanol to prepare solutions for experimental use.

Melting point (Celsius)
267.00
Melting point (Kelvin)
540.15
Boiling point (Celsius)
500.00
Boiling point (Kelvin)
773.15
General information
Molecular weight
393.27g/mol
Molar mass
393.2700g/mol
Density
1.1000g/cm3
Appearence

Acridine Orange appears as an orange to dark orange powder at room temperature. It is often used in a fluorescent dye form, where it exhibits a green or red fluorescence depending on the pH and the nature of the substances it binds to.

Comment on solubility

Solubility of 3-(acridin-9-ylammonio)propyl-dimethyl-ammonium; dichloride

The solubility of 3-(acridin-9-ylammonio)propyl-dimethyl-ammonium; dichloride is a topic of considerable interest due to its unique structure and applications. Understanding the solubility characteristics of this compound can reveal much about its behavior in various environments.

Key Points on Solubility

  • Water Solubility: This compound is expected to be soluble in water due to the presence of its quaternary ammonium structure, which typically enhances solubility in polar solvents.
  • Solvent Effects: Its solubility might vary significantly in non-polar solvents or organic solvents, thus making it more soluble in polar aprotic solvents.
  • Temperature Dependence: Like many ionic compounds, solubility can be affected by temperature; increasing temperature may improve solubility.
  • pH Influence: Changes in pH could impact the ionization of the compound, consequently influencing its aqueous solubility.

It is important to note that the solubility of this compound can be quantified and predicted through various models, but real-world dissolution may also be influenced by external factors such as ionic strength and the presence of other solutes in solution.

For practical applications, solubility data is crucial; for instance, high solubility in biological media would indicate potential usefulness in pharmaceuticals and other biological applications. In contrast, poor solubility could limit its effectiveness in these areas.

Interesting facts

Interesting Facts about 3-(Acridin-9-ylammonio)propyl-dimethyl-ammonium; Dichloride

This unique compound showcases a fascinating interplay of organic chemistry and medicinal properties. Here are some intriguing aspects:

  • Structure and Function: The compound is characterized by its acridine moiety, which is a component that often exhibits noteworthy biological activity. Acridine derivatives have gained significance in the realm of pharmaceuticals, particularly in anti-cancer therapies.
  • Quaternary Ammonium Salts: As a quaternary ammonium salt, this compound exhibits cationic properties that can be beneficial for various applications, such as antimicrobial agents and drug delivery systems.
  • Enhanced Solubility: The presence of the dimethylammonium group contributes to enhanced solubility in aqueous environments, making it potentially useful for formulations in medicinal chemistry.
  • Potential Applications: Research has indicated that compounds with this type of architecture may play roles in gene delivery and biological imaging, showcasing their versatility beyond traditional uses.
  • Biological Interaction: The acridinyl structure may facilitate intercalation within nucleic acids, a mechanism that is essential for various therapeutic agents targeting DNA.

In summary, 3-(acridin-9-ylammonio)propyl-dimethyl-ammonium; dichloride is a remarkable compound that highlights the intersections of structure and application in medicinal chemistry. Its potential in modern therapeutic approaches makes it an exciting subject of study for chemists and researchers alike.

Synonyms
1092-03-1
ACRIDINE, 9-((3-(DIMETHYLAMINO)PROPYL)AMINO)-, DIHYDROCHLORIDE
3-(acridin-9-ylazaniumyl)propyl-dimethylazanium;dichloride
AI 3-63044
NSC 109329
AI3-63044
1,3-Propanediamine, N'-9-acridinyl-N,N-dimethyl-, dihydrochloride